Effects of endurance training on exhaustive exercise-induced oxidative stress markers

Abstract

This study was aimed to investigate the effects of endurance training on lipid peroxidation and antioxidant enzyme levels in young adults. Twenty four male students participated in this study. Subjects were divided into two groups as training group (n=12) and control group (n=12). Subjects in the training groups performed running exercise 25 to 60 min/day, three days/week for eight weeks at an intensity of 50 to 70% of target heart rate. Blood samples collected at rest and after exhaustive exercise before and after 8 weeks, were analyzed for the determination of plasma lipid hydroperoxide (LOOH) level, and activities of glutathione peroxidase (GPx), catalase (CAT) and lactate dehydrogenase (LDH). LOOH level in the training group significantly decreased after the post-training period (p<0.05), but did not alter in the control group (p>0.05). LDH activities significantly increased both control and training groups after the exhaustive exercise (p<0.05). LDH activity was found significantly higher in control group than training group both at rest and after exhaustive exercise (p<0.05). GPx was not significantly altered by training and exhaustive exercise in both groups (p>0.05). In the training group, exhaustive exercise significantly increased CAT level after training period (p<0.05). Consequently, it can be said that endurance training is effective in prevention of lipid peroxidation caused by exhaustive exercise.

Associations between bio-motor ability, endocrine markers and hand-specific anthropometrics in elite female futsal players: a pilot study

“…To estimate aerobic power by maximal oxygen consumption values (VO 2max ), the Bruce treadmill protocol was used [ 30 ]. Briefly, participants ran on a treadmill completing an exhaustive running test.…”

Different Protocols of Physical Training: Effect on Markers of Oxidative Stress in Erythrocytes in Rats

“…The beneficial effects of aerobic exercise training on antioxidant defense mechanisms in several tissues have been reported [12] [18]. Revan and Erol [19] have observed in subjects who performed a protocol of physical training in the intensity of 50% to 70% of maximum heart rate. It was able to reduce the levels of lipid peroxidation in erythrocytes after exhaustive exercise.…”

Supplementation of Garcinia mangostana Linn and Vasconcellea pubescens A.DC extract reduced exercise-induced oxidative stress in rats

“…The group of rats given a combination dose of GME and VPE with a ratio of 75:25 and 50:50 showed the same and significantly different reduction in MDA when compared to a dose of 25:75. Increased levels of MDA in the control group due to the production of free radicals caused by physical activity exceeds the body's antioxidant cellular defense resulting in oxidative stress (Jackson et al, 2016;Revan and Erol, 2011). As is known Malondialdehyde (MDA) is one of the results of lipid peroxidation caused by free radicals during maximum physical exercise or endurance training with high intensity (Tsikas, 2017).…”

“…Oxidative stress conditions also affect the hematological profile (Abdel-Moneim et al, 2019a), which is thought to be due to the release of inflammatory mediators (Boskabady and Farhadi, 2008). Aerobic exercise can increase oxygen consumption 10-20 times in the body and 100-200 times in skeletal muscle (Revan and Erol, 2011). Several recent investigations have found that NADPH oxidase enzymes in the skeletal play a signaling role in physiological responses to exercise and that they, together with xanthine oxidase enzymes, may contribute to the relative increase in whole-body oxidation (Jackson et al, 2016).…”