1983
DOI: 10.1159/000206685
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Effects of Ethanol on Cell Volume and Protein Synthesis in a Human Lymphoblastoid Cell Line (Raji)

Abstract: A human lymphoblastoid cell line (Raji) developed macrocytosis after 5–7 days when cultured in the presence of 100, 250 and 500 mg ethanol/dl. The degree of macrocytosis was least with 100 mg/dl and greatest with 500 mg/dl. The macrocytosis was associated with a proportionate increase in the total protein content per cell, was reversed after culture in the absence of ethanol and was uninfluenced by the supplementation of the culture medium with 50 μg folic or folinic acids per millilitre. Ethanol also caused a… Show more

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Cited by 5 publications
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