2014
DOI: 10.3389/fphys.2014.00051
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Effects of exercise on cardiovascular performance in the elderly

Abstract: Progressive aging induces several structural and functional alterations in the cardiovascular system, among whom particularly important are a reduced number of myocardial cells and increased interstitial collagen fibers, which result in impaired left ventricular diastolic function. Even in the absence of cardiovascular disease, aging is strongly associated to a age-related reduced maximal aerobic capacity. This is due to a variety of physiological changes both at central and at peripheral level. Physical activ… Show more

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Cited by 89 publications
(67 citation statements)
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“…It is a dynamic and progressive process in which changes occur, both morphological, functional, and biochemical and psychological which determine the progressive loss of the individual's ability to adapt to the environment, leading to greater vulnerability and greater incidence of pathological processes [1,2].…”
Section: Introductionmentioning
confidence: 99%
“…It is a dynamic and progressive process in which changes occur, both morphological, functional, and biochemical and psychological which determine the progressive loss of the individual's ability to adapt to the environment, leading to greater vulnerability and greater incidence of pathological processes [1,2].…”
Section: Introductionmentioning
confidence: 99%
“…In turn this could lead to an increase in overall quality of life and a consequent reduction in healthcare use. In addition, exercise is of great importance for cardiovascular (Vigorito 2014) and bone health (Sakuma 2012). Reduced physical function and consequent lack of mobility in people with chronic pain is associated with increased all-cause and cardiovascular mortality (Nüesch 2011), with other studies linking severe chronic pain to general increased all-cause mortality (Moore 2014a; Torrance 2010).…”
Section: Introductionmentioning
confidence: 99%
“…It is well-documented that traditional pharmacological and surgical therapies do not adequately address all of the impairments in PD [4]. Exercise has been shown to improve motor impairments in aging populations [57], and may be especially important for people with PD due to emerging evidence supporting potential neuroprotective effects [8]. …”
Section: Introductionmentioning
confidence: 99%