1990
DOI: 10.1016/0041-008x(90)90222-g
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Effects of exposure to benzene in vivo on the murine mononuclear phagocyte system*1

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Cited by 10 publications
(2 citation statements)
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“…Benzene depresses B and T lymphocytes as well as their mitogenic responses (Rozen & Snyder, 1985). Mice treated with benzene by subcutaneous injection displayed fewer peritoneal macrophages, decreased phagocytic and tumor-cell cytolysis capability, and increased hydrogen peroxide generation (Klan et al, 1990). Mice treated with benzene by subcutaneous injection displayed fewer peritoneal macrophages, decreased phagocytic and tumor-cell cytolysis capability, and increased hydrogen peroxide generation (Klan et al, 1990).…”
mentioning
confidence: 99%
“…Benzene depresses B and T lymphocytes as well as their mitogenic responses (Rozen & Snyder, 1985). Mice treated with benzene by subcutaneous injection displayed fewer peritoneal macrophages, decreased phagocytic and tumor-cell cytolysis capability, and increased hydrogen peroxide generation (Klan et al, 1990). Mice treated with benzene by subcutaneous injection displayed fewer peritoneal macrophages, decreased phagocytic and tumor-cell cytolysis capability, and increased hydrogen peroxide generation (Klan et al, 1990).…”
mentioning
confidence: 99%
“…These tables include information on the immune category evaluated by each test, organs, cells, or other targets, principal effects on the immune system, doses, routes of exposure for each specific assay. References for each study and specific to the organizations that recommend or mention the use of these tests, and, when considered, the [Li, 1992] a Body weight: upto100 mg/kg/day,12 months or2 years, (oral) in rats [NTP, 1986] Cellularity (spleen) T-cell: at 31ppm, 6 days, and at 300 ppm, 2^5 weeks, (inhalation) in mice [Rozen et al, 1984] Cellularity (bone marrow): at 25 ppm, 2 weeks Cellularity B,Tand Tcell subset (spleen): at100 ppm, 20 days (inhalation) in mice [Rosenthal and Snyder, 1987] Cellularity B lymphocytes (bone marrow): at10 ppm, 6 days, (inhalation) in mice [Rozen et al,1984] Cellularity (bone marrow) at 25 ppm, 2 weeks (inhalation) in mice [Cronkite et al, 1985] Cellularity ( Wells and Nerland [1991] (2) Klan et al [1990] (b) Aoyama [1986] (c) Aksoy et al [1987] a (d) Aksoy et al [1971Aksoy et al [ , 1972Aksoy et al [ ,1974 a (e) (1) Mitogenic response (T-cell) lymphocyte to PHA (peripheral blood): (occupational) humans [Yardley-Jones et al,1988] PFC to SRBC: at 400 ppm, 2 or 4 weeks (inhalation) in rats Host resistance s. zooepidemicus: at10 ppm, 1or 5 days (inhalation in mice) [Aranyi et al, 1989] (a) Macrophage activity (bone marrow) Rozen et al [1984] (b) Rozen and Snyder [1985] (c) Hsieh et al [1990] Surface markers:…”
Section: Resultsmentioning
confidence: 99%