Effects of extended-release eprinomectin on productivity measures in cow-calf systems and subsequent feedlot performance and carcass characteristics of calves

Andresen, Claire; Loy, Daniel D.; Gunn, Patrick J.; Brick, T. A.

doi:10.31274/air.6800

Cited by 2 publications

(10 citation statements)

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“…The ERE-treated heifers had less FEC compared to the control heifers and had similar FEC compared to the combination dosed heifers at all times except for d 84 ( Backes et al, 2015 ). In a large experiment by Andresen et al (2018) using 13 herds from seven states, there was no difference in BW change or ADG between cows treated with extended-release eprinomectin and doramectin. Cattle in this experiment were all treated with an anthelmintic and had low FEC (<3 EPG), but forage source was not mentioned ( Andresen et al, 2018 ).…”

Section: Discussionmentioning

confidence: 91%

“…In a large experiment by Andresen et al (2018) using 13 herds from seven states, there was no difference in BW change or ADG between cows treated with extended-release eprinomectin and doramectin. Cattle in this experiment were all treated with an anthelmintic and had low FEC (<3 EPG), but forage source was not mentioned ( Andresen et al, 2018 ). In the current experiment, all cattle were dosed with oral fenbendazole (Safe-Guard) 2 weeks prior to experiment initiation and FEC remained low throughout the duration of the study.…”

Section: Discussionmentioning

confidence: 91%

“…Horn flies are one of the most common ectoparasites that can negatively affect animal performance ( Byford et al, 1992 ). Previous literature has indicated extended-release eprinomectin may have some level of fly control ( Vesco et al, 2015 ; Trehal et al, 2017 ); however, other studies have not noted improvements in fly control in cows ( Andresen et al, 2018 ). In this current experiment, it is important to remember that all cattle were comingled and horn fly differences were not anticipated as partial-treated herds have seen reduction in horn flies in both treated and untreated cattle ( Harvey and Brethour, 1983 ).…”

Section: Discussionmentioning

confidence: 95%

“…In a large experiment, using 13 herds from seven states, no differences in pregnancy rates were noted between cows treated with extended-release eprinomectin and injectable doramectin ( Andresen et al, 2018 ). Both groups were treated with an anthelmintic and FEC reported for this experiment were low (<3 EPG); however, forage source was not reported ( Andresen et al, 2018 ).…”

Section: Discussionmentioning

confidence: 99%

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Effects of spring administration of extended-release eprinomectin on fescue toxicosis, performance, and reproduction of fall-born beef heifers

Volk

Kordas

Stokes

et al. 2019

Translational Animal Science

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The objective of this experiment was to assess the effects of eprinomectin, an extended-release injectable parasiticide, on fescue toxicosis and its impacts on beef heifer performance and reproduction. Fall-born Angus × Simmental heifers (age = 246.3 ± 22.4 d; 264.8 ± 21.1 kg body weight [BW]) were randomly assigned to one of two treatments: extended-release eprinomectin injection (ERE; n = 100) or control (CON; saline; n = 99). Treatments were administered at a rate of 1 mL/50 kg BW. Prior to experiment, heifers were dosed with oral fenbendazole to minimize parasite load. All heifers grazed endophyte-infected tall fescue as a single group and were offered a 50:50 supplement mix of corn gluten feed and soybean hulls (2.7 kg as fed per heifer per day). Body condition scores (BCS), BW, hair coat score (HCS), blood, and fecal samples were collected throughout the experiment. A subset of 40 heifers were randomly selected (20 per treatment) to assess respiration rate (RR). On d 138, heifers began a 14-d controlled internal drug release + prostaglandin synchronization protocol. Following artificial insemination (AI), heifers were exposed to five bulls for 71 d. On d 214 and 291, AI and overall pregnancy rates, respectively, were determined. There was a treatment × time interaction (P < 0.01) for BW, BCS, and average daily gain (ADG). The ERE heifers had greater (P < 0.04) BW and BCS compared to CON heifers from d 55 and 112, respectively. In addition, ERE heifers had greater (P ≤ 0.04) ADG from d 0 to 56, 56 to 112, 112 to 171, and 171 to 214; however CON heifers had greater (P < 0.01) ADG from d 214 to 291. There was no treatment × time interaction or treatment difference (P ≥ 0.27) for HCS, RR, and serum prolactin concentrations. However, serum prolactin decreased (P < 0.01) in all heifers over time. There was a treatment × time interaction (P<0.01) for fecal egg counts (FEC). The FEC did not differ (P ≥ 0.32) on d −1 or 55; however, ERE heifers had decreased (P < 0.01) FEC compared with CON heifers on d 111 (1.52 vs. 13.56 eggs per gram). The ERE heifers tended (P = 0.10) to have greater AI pregnancy rates (69% vs. 58%) and had greater (P = 0.01) overall pregnancy rates (84% vs. 68%) than CON heifers. Spring administration of extended-release eprinomectin improved BW, ADG, BCS, and AI and overall pregnancy rates in fall-born beef heifers. However, the underlying mechanism is still unclear, as there were minimal to no differences in HCS, RR, serum prolactin, and FEC.

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Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Effects of spring administration of extended-release eprinomectin on fescue toxicosis, performance, and reproduction of fall-born beef heifers

Volk

Kordas

Stokes

et al. 2019

Translational Animal Science

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“…Additionally, previous research has shown no differences in cow body weight (BW) or reproductive performance when spring-calving cows were treated with extended-release eprinomectin compared to cows administered a different anthelmintic or untreated controls ( Backes, 2016 ; Andresen et al, 2018b ). To our knowledge, there is no published literature on the effects of fall-calving cows grazing endophyte-infected tall fescue when treated with extended-release eprinomectin.…”

Section: Introductionmentioning

confidence: 99%

Effects of extended-release eprinomectin on fescue toxicosis, performance, and reproduction on fall-calving beef cows

Volk

Krause

Stokes

et al. 2019

Translational Animal Science

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The objective of this experiment was to evaluate effects of extended-release eprinomectin on fescue toxicosis and impacts on performance and reproduction in fall-calving beef cows. Fall-calving Angus × Simmental multiparous cows [n = 335; age = 5.8 ± 2.1 yr; 586.5 ± 6.0 kg body weight (BW); 5.48 ± 0.05 body condition score (BCS)] were stratified by BW, age, and BCS and randomly assigned to one of three treatments. Treatments included a spring injection of extended-release eprinomectin (SERE) on day 0, a fall injection of extended-release eprinomectin injection (FERE) on day 84, and a saline control (CON). All treatments were administered at a rate of 1 mL/50 kg BW. Prior to the experiment, all cows were treated with oral fenbendazole to minimize parasite load. Cows grazed endophyte-infected tall fescue. Hair coat score (HCS), BW, and BCS were recorded on all cattle. Fecal egg count (FEC), respiration rate (RR), horn fly and tick count, hematocrit (% packed cell volume, PCV), and serum prolactin were analyzed on a subset of cows (35/treatment). On day 194, cows were artificially inseminated (AI) and 11 d following AI were exposed to bulls for 51 d. Milk production was estimated on day 210 on a subset of 85 cow–calf pairs (28–29/treatment). There was a tendency for a treatment × time interaction (P = 0.07) for FEC likely driven by an increase in FEC of the CON cattle at day 126 compared to SERE and FERE. There was a tendency for a treatment × time interaction (P = 0.06) for cow BW, largely driven by time differences; however, there was no effect of treatment (P = 0.84) on BW. There was no difference (P ≥ 0.13) in cow PCV, fly and tick count, BCS, HCS, RR, and serum prolactin throughout the experiment. Additionally, there was no difference (P ≥ 0.46) in Julian calving date, calf birth BW, or milk production between treatments. Interestingly, heifer calves born to FERE dams tended to have greater (P = 0.06) weaning BW compared to heifer calves born to CON dams. In addition, there was no difference (P ≥ 0.17) in heat patch scores, AI conception rates, or overall pregnancy rates between treatments. Extended-release eprinomectin did not impact cow growth performance, reproductive performance or fescue toxicity symptoms when grazing endophyte-infected tall fescue; however, calf weaning BW tended to be improved.

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Effects of extended-release eprinomectin on productivity measures in cow-calf systems and subsequent feedlot performance and carcass characteristics of calves

Cited by 2 publications

References 0 publications

Effects of spring administration of extended-release eprinomectin on fescue toxicosis, performance, and reproduction of fall-born beef heifers

Effects of spring administration of extended-release eprinomectin on fescue toxicosis, performance, and reproduction of fall-born beef heifers

Effects of extended-release eprinomectin on fescue toxicosis, performance, and reproduction on fall-calving beef cows

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