Effects of extracorporeal circulation with different time on platelet count after cardiac surgery: A retrospective study based on medical records

Abstract

Background Our objective was to observe the effects of extracorporeal circulation (ECC) with different time on platelet count in patients undergoing cardiac surgery. Methods A total of 427 patients who underwent elective cardiac surgery under ECC in affiliated hospital of north Sichuan medical college from January 1, 2018 to July 31, 2021 were divided into three groups according to ECC time. Their data were collected from the Do care and electronic medical record information system. All authors confirm that all methods were performed in accordance with the relevant guidelines and regulations. Results At the end of operation, platelet count was significantly lower in group C than in group A (p< 0.05); on the first day after operation, platelet count was significantly higher in groups A and B than in group C (p< 0.05); compared with group A, platelet count on the second day and the fifth day after operation were significantly lower in groups B and C (p< 0.05). The mean platelet volume (MPV) was significantly reduced at the end of operation in each group (p< 0.05). The absolute monocyte count at the end of operation was significantly higher in group C than in groups A and B (p< 0.05). The volume of blood loss and plasma transfusion were significantly lower in group A than in groups B and C (p< 0.05). Conclusion Platelet count in patients undergoing cardiac surgery after ECC was reduced significantly, which was more serious with the extension of ECC time. The recovery level and speed of platelet count in patients with long ECC time were lower than those with short ECC time.