Effects of faba beans (Vicia faba L.) on growth performance, textural quality and physiological indices of tilapia (Oreochromis niloticus)

Li, Qingqing; Huang, Yao; Zhang, Xingqian; Qin, Zhendong; Zou, Cuiyun; Tan, Xiao; Xie, Xi; Liang, Shaowen; Li, Lin

doi:10.1016/j.aquaculture.2023.739640

Cited by 5 publications

(1 citation statement)

References 30 publications

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“…In our study, the decrease in the number and structural disorganization of mitochondria in CGC liver, together with the down‐regulation of structurally related proteins (neb, tmod4, ela2l, tnnc2, and ttna), could be the result of the increase in ROS induced by broad bean. In addition, the phenomenon of oxidative stress induced by broad bean has been similarly found in several tissues in several animals, such as Yellow River carp ( Cyprinus carpio ) (Song et al., 2022) and tilapia ( Oreochromis niloticus ) (Li et al., 2023). It has now been shown that broad bean contains a number of pro‐oxidant ANFs, such as vicine, convicine, and tannins (Ortiz et al., 1994; Sharan et al., 2021).…”

Section: Discussionmentioning

confidence: 99%

Broad bean (Vicia faba L.) caused abnormal lipid metabolism in grass carp (Ctenopharyngodon idellus) liver: Insight from the gut microbiota–liver axis

Fu,

Ma,

Yang

et al. 2024

Food Frontiers

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Broad bean (Vicia faba L.) has received attention from the food and animal feed industries as a sustainable, inexpensive, and versatile plant‐based protein source. However, long‐term consumption of broad bean, especially unprocessed ones, can lead to hepatic lipid accumulation. To investigate how broad bean affected hepatic lipid metabolism and its underlying mechanisms, we conducted a multi‐omics analysis of crisp grass carp (Ctenopharyngodon idellus C. et V) model with hepatic steatosis after feeding with single broad bean for 120 days. The glycolysis inhibition, increased de novo lipogenesis, abnormalities in lipid metabolism, and activation of oxidative stress were the key processes involved in broad bean‐induced hepatic lipid accumulation. Disturbances in intestinal flora caused by damage to the intestinal barrier and increased lipopolysaccharide caused by broad bean promoted hepatic lipid accumulation. Reduction of antinutritional factors and balanced diet offer potential strategies to mitigate the liver damage caused by broad bean consumption. Overall, our findings provided a theoretical basis for the wide application of broad bean as animal feeds.

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