Effects of Fermented Soybean Meal on Immune Response of Weaned Calves with Experimentally Induced Lipopolysaccharide Challenge

Abstract

The present study was conducted to evaluate the effects of fermented soybean meal (FSBM) on the level of cortisol hormone and immune-related serum proteins in weaned calves after experimentally induced lipopolysaccharide (LPS) challenge. Holstein neonatal calves (n = 21; 8 males and 13 females, BW = 42.2±6.15 kg) were randomly allocated to one of two dietary treatments: SBM (control calf starter having soybean meal (SBM) as a main protein source) and FSBM (substitute SBM in control diet with FSBM) groups. All calves were fed milk replacer using an automatic milk-feeder according to step-down milking method and weaned at 7 weeks old. Experimental diets were given to calves ad libitum throughout the experimental period. For LPS challenge, all calves except negative control animals given phosphate buffered saline (PBS), were injected subcutaneously with Salmonella typhimurium LPS on day 7 (D7) after weaning (D0). No significant difference in growth performance and milk intake was observed between SBM and FSBM calves. Feeding FSBM diet resulted in significantly (p<0.05) higher LPS-specific IgG at D12 and D19 and LPS-specific IgA at D19 in peripheral blood. Calves fed with FSBM diet also had significantly (p<0.05) higher concentration of serum haptoglobin (Hp) at D8. Overall concentration of cortisol in FSBM group was considerably lower than that of SBM group. Results from current study indicate that FSBM may provide beneficial effects in alleviating weaning stress and enhance immune status of weaned calves.

Role of Fermentation in Improving Nutritional Quality of Soybean Meal — A Review

“…The beneficial effects of feeding FSBM based diets to a variety of ruminants as well as non-ruminants, both young and adult, have also been investigated and established (Mathivanan et al, 2006; Song et al, 2008; Yuan et al, 2012). Increase in the majority of growth promoting factors as well as health parameters are seen in farm and poultry animals (Feng et al, 2007a, b; Liu et al, 2007; Kwon et al, 2011). FSBM based diet is also recommended for certain fish species as a replacement of fish meal in several studies (Yamamoto et al, 2010; Kader et al, 2012; Yuan et al, 2012).…”

USING A DIGESTAMIN AS A FEED ADDITIVE IN EGYPTIAN BUFFALO COWS (Bubalus bubalis) DIETS

“…On the other hand, there was a significant decrease (P<0.01) in blood, glucose, AST and ALT concentration with increasing digestamin levels. Kwon et al (2011) showed that, total serum Ig A and IgM levels significantly increased in both FSBM groups compared to un supplemented one. It could be suggest that, FSBM may have lower concentrations of allergenic and anti nutritional factors than the soybean meal which improve kidney and liver function of experimental animals (Wolfswinke, 2009).…”

Peptide supplementation to nutrient‐adequate diets enhanced internal egg quality during storage in hens at peak production

“…From an animal nutrition point of view, it has been suggested that feeding of peptides or fermented or enzymatically hydrolysed protein feedstuffs improved growth performance, is an effective way of meeting amino acid requirements in low‐protein diets and influences endogenous amino acid loses . Aside from nutritional effects, though, peptides also serve functional food roles and help to enhance gut health or reduce stress response . However, there is a scarcity of reports on the supplementation of peptides in poultry diets.…”