Effects of Fluid and Dobutamine Treatment on Renal Function during Partial Superior Mesenteric Artery Occlusion and Reperfusion

Heino, Antero; Merasto, Minna E.; Koski, Erkki M. J.; Juvonen, Petri; Alhava, Esko; Hartikainen, Juha

doi:10.1080/003655902317259292

Cited by 4 publications

(3 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Investigators have reported divergent results for other species. In dogs, 44 pigs, 45 and humans, 46,47 dobutamine infusion did not increase GFR or renal blood flow in adult patients or healthy volunteers. Conversely, studies in newborn pigs 48,49 and human neonates 50 revealed an increase in renal arterial blood flow in response to dobutamine infusion.…”

Section: Discussionmentioning

confidence: 79%

Effects of meloxicam and phenylbutazone on renal responses to furosemide, dobutamine, and exercise in horses

Raidal

Hughes

Charman

et al. 2014

ajvr

View full text Add to dashboard Cite

Responses to meloxicam, a cyclooxygenase (COX)-2 preferential agent, appeared comparable to those detected after phenylbutazone treatment, which suggested that COX-2 was the mediator of prostanoid-induced changes to renal function in horses and indicated that COX-2-preferential agents would be likely to have adverse renal effects similar to those for nonselective COX inhibitors in volume-depleted horses.

show abstract

Section: Discussionmentioning

confidence: 79%

Effects of meloxicam and phenylbutazone on renal responses to furosemide, dobutamine, and exercise in horses

Raidal

Hughes

Charman

et al. 2014

ajvr

View full text Add to dashboard Cite

show abstract

“…Several researchers have shown that hepatic and pulmonary dysfunction may occur after mesenteric I/R [1,9]. However, the effect of mesenteric I/R on the kidney has received relatively little attention [14–19]. LaNoue et al.…”

Section: Discussionmentioning

confidence: 99%

“…The effect of intestinal I/R on lipid peroxidation in rat kidney tissue has not been thoroughly investigated. Accumulating evidence suggests that renal dysfunction may occur after intestinal I/R [14–19]. In the present study, we investigated (1) the presence of oxLDL in renal tissue after intestinal I/R and (2) the association between oxLDL and iNOS expression and superoxide dismutase (SOD) activity in renal damage.…”

Section: Introductionmentioning

confidence: 99%

The presence of oxidized low‐density lipoprotein and inducible nitric oxide synthase expression in renal damage after intestinal ischemia reperfusion

Yurdakan

Tekin

Comert

et al. 2011

The Kaohsiung J of Med Scie

View full text Add to dashboard Cite

Intestinal ischemia/reperfusion (I/R) is a complex phenomenon that causes destruction of both local and remote tissues. The objective of this study was to investigate the possible participation of oxidized low-density lipoproteins (oxLDLs) and inducible nitric oxide synthase (iNOS) expression in renal tissue damage after intestinal I/R. The superior mesenteric artery was blocked for 30 minutes, followed by 24 hours of reperfusion. At the end of the reperfusion period, renal tissues were removed; the presence of oxLDL, superoxide dismutase enzyme activity, malondialdehyde levels, and iNOS expression were evaluated. I/R resulted in positive oxLDL staining in renal tissue. Compared with control rats, tissue from the I/R group showed significantly higher malondialdehyde levels and lower superoxide dismutase enzyme activity. Strong and diffuse iNOS expression was present in the I/R group. Our findings support the hypothesis that I/R of intestinal tissue results in oxidative and nitrosative stress and enhances lipid peroxidation in the end organ. These data show that oxLDL accumulates in rat renal tissue after intestinal I/R. Antioxidant strategies may provide organ protection in patients with reperfusion injury, at least by affecting interactions with free radicals, nitric oxide, and oxLDL. This study demonstrates for the first time that oxLDL may play a role in renal tissue damage after intestinal I/R. Antioxidant strategies may be beneficial for protection from reperfusion injury.

show abstract

Ringer’s ethyl pyruvate solution attenuates hypoperfusion and renal injury after multivisceral ischemia–reperfusion in rabbits

et al. 2020

View full text Add to dashboard Cite

Effects of Fluid and Dobutamine Treatment on Renal Function during Partial Superior Mesenteric Artery Occlusion and Reperfusion

Cited by 4 publications

References 35 publications

Effects of meloxicam and phenylbutazone on renal responses to furosemide, dobutamine, and exercise in horses

Effects of meloxicam and phenylbutazone on renal responses to furosemide, dobutamine, and exercise in horses

The presence of oxidized low‐density lipoprotein and inducible nitric oxide synthase expression in renal damage after intestinal ischemia reperfusion

Ringer’s ethyl pyruvate solution attenuates hypoperfusion and renal injury after multivisceral ischemia–reperfusion in rabbits

Contact Info

Product

Resources

About