Effects of follicular fluid-derived extracellular vesicles improve in vitro maturation and embryonic development of porcine oocytes
Heejae Kang,
Seonggyu Bang,
Heyyoung Kim
et al.
Abstract:To optimize the most efficient method for porcine in vitro maturation (IVM), we compared the effects of supplementing extracellular vesicles (EVs) derived from porcine follicular fluid (pFF). The cumulus oocyte complexes were grouped into 4 groups with different supplementations as following: pFF (G1), pFF-depleted EVs (G2), EVs (G3) and control (G4) groups. After IVM with different supplementations, maturation rates and the developmental competences of porcine oocytes and blastocyst development were investiga… Show more
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