Effects of food deprivation on expression of growth hormone receptor and proximate composition in liver of black seabream Acanthopagrus schlegeli

Deng, Liyu; Zhang, W.M.; Lin, Haoran; Chen, Cheng

doi:10.1016/j.cbpc.2004.01.008

Cited by 60 publications

(25 citation statements)

References 44 publications

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“…In the presently reported study, the insignificant depletion observed in plasma T 4 levels with extending the starvation period (8 days starvation) is probably due to reduced T 4 release from the thyroid tissue in juvenile Siberian sturgeon. This adjustment of TH homeostasis during starvation is in broad agreement with previous studies in numerous fish species (Holloway et al 1994, Van der Geyten et al 1998, Leiner et al 2000, De Pedro Deng et al 2004, Raine et al 2005, which has been known as the lowered anabolic capacity of the animal and the mobilization of stored energy reserves. Gaylord et al (2001) expressed that the reason for the low TH (T 3 and T 4 ) concentrations in channel catfish, Ictalurus punctatus (Rafinesque, 1818), during a 3-day starvation period is the diminished sensitivity of the thyroid tissue to thyroid stimulating hormone (TSH).…”

Section: Discussionsupporting

confidence: 91%

The Effect of Short-term Starvation on Some Physiological and Morphological Parameters in Juvenile Siberian Sturgeon, Acipenser Baerii (Actinopterygii: Acipenseriformes: Acipenseridae)

Ashouri¹,

Yavari²,

Bahmani³

et al. 2013

Acta Icth et Piscat

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Section: Discussionsupporting

confidence: 91%

The Effect of Short-term Starvation on Some Physiological and Morphological Parameters in Juvenile Siberian Sturgeon, Acipenser Baerii (Actinopterygii: Acipenseriformes: Acipenseridae)

Ashouri¹,

Yavari²,

Bahmani³

et al. 2013

Acta Icth et Piscat

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“…In muscle both GHR mRNA abundances were restored after 4 days. A recent study performed in black seabream (Acanthopagrus schlegeli) reported a lower GHR mRNA level in liver of starved fish (Deng et al 2004). This apparent discrepancy between these data and ours could be related to species differences as well as to the environmental conditions, since water temperature and salinity were not tightly controlled in the Deng et al study.…”

Section: Discussioncontrasting

confidence: 55%

“…In contrast, hepatic GH-binding capacities are lowered after several weeks of starvation (Gray et al 1992, Pérez-Sánchez et al 1994. Recently, it was shown that starvation decreased the expression of GHR mRNA in the liver (Deng et al 2004, Fukada et al 2004, but the effect of starvation on the gene expression of the two GHRs present in salmonids is unknown. It has been hypothesized that the hepatic resistance to GH would partly account for the low plasma levels of IGF-I observed in starved fish (Pérez-Sánchez et al 1995, Baños et al 1999, Shimizu et al 1999 and that the increase in GH levels results from the decline of IGF-I feedback on GH cells.…”

Section: Introductionmentioning

confidence: 99%

Coordinated regulation of the GH/IGF system genes during refeeding in rainbow trout (Oncorhynchus mykiss)

Gabillard¹,

Kamangar²,

Montserrat³

2006

Journal of Endocrinology

180

122

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The GH/IGF system is a complex regulation network strongly dependent on nutrient availability. While the effect of starvation on the GH/IGF system has been extensively studied, the time course of events leading to the restoration of GH/IGF system activity after starvation is largely unknown. We, therefore, measured the plasma levels of GH, IGF-I and IGF-II and the expression of the GH/IGF system in liver and muscle. Starvation increased the plasma GH level and 1 day of refeeding completely restored it (1$10G0$27 vs 1$12G0$28 ng/ml). Thereafter, plasma GH continued to decrease until day 7 and returned to control values from day 15. Starvation decreased plasma IGF-I and IGF-II and refeeding raised plasma IGF-I only from day 4. In contrast, the plasma IGF-II level doubled after 1 day's refeeding (26$5G1$9 vs 44$0G3$4 ng/ml; P!0$01). Starved fish exhibited higher GH receptor (GHR)1 mRNA abundance in liver and muscle than in controls, whereas GHR2 mRNA abundance was increased only in muscle. In liver, 1 day of refeeding, decreased GHR1 (twofold), but increased GHR2 mRNA abundance (twofold). Thereafter, a progressive return to normal values was observed. Liver IGFBP-4 mRNA abundance was lowered in starved fish followed by a progressive restoration during refeeding. Starvation had no effect on liver IGFBP-2 and IGFBP-6 mRNA abundance, whereas refeeding provoked a peak of IGFBP-2 and IGFBP-6 expression at day 7. In muscle, starvation led to a decrease of the IGFBP-2 mRNA level, which was restored only from day 7. IGFBP-4 mRNA abundance in starved fish was lower than in the controls and refeeding led to a transient upregulation (sevenfold) of IGFBP-4 gene at day 1. IGF-I, IGFBP-5, and IGFBP-related protein 1 (rP1) expression profiles were similar, showing a decrease of expression after starvation, a first peak of expression at day 2, a second peak at day 7, and a return to normal value from day 15. Moreover, IGF-I, IGFBP-5, and IGFBP-rP1 mRNA abundance were positively correlated (rZ0$6-0$8; P!0$0001). In conclusion, plasma IGF-I was restored later than plasma GH level, which suggests that plasma IGF-I levels cannot account for plasma GH changes. The coordinated regulation of IGF-I, IGFBP-5, and IGFBP-rP1 expression would be a signature for the resumption of myogenic activity.

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“…The time of tissue sampling could be a possible reason since temporal variation in GHR expression has been reported in some fish species (Wargelius et al 2005). The extent of feeding is another possibility since satiety and starvation could affect GHR expression (Deng et al 2004, Fukada et al 2004.…”

Section: Discussionmentioning

confidence: 99%

The co-existence of two growth hormone receptors in teleost fish and their differential signal transduction, tissue distribution and hormonal regulation of expression in seabream

Jiao

Huang²,

Chan³

et al. 2006

Journal of Molecular Endocrinology

151

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Two genomic contigs of putative growth hormone receptors (GHRs) were identified in fugu and zebrafish genomes by in silico analysis, suggesting the presence of two GHR subtypes in a single teleost species. We have tested this hypothesis by cloning the full-length cDNA sequence of a second GHR subtype from the black seabream in which the first GHR subtype had been previously reported by us. In addition, we had also cloned the sequences of both GHR subtypes from two other fish species, namely the Southern catfish and the Nile tilapia. Phylogenetic analysis of known GHR sequences from various vertebrates revealed that fish GHRs cluster into two distinct clades, viz. GHR1 and GHR2. One clade (GHR1), containing 6 to 7 extracellular cysteine residues, is structurally more akin to the non-teleost GHRs. The other clade (GHR2), containing only 4 to 5 extracellular cysteine residues, is unique to teleosts and is structurally more divergent from the non-teleost GHRs. In addition, we had examined the biological activities of both GHR subtypes from seabream using a number of reporter transcription assays in cultured eukaryotic cells and demonstrated that both of them were able to activate the Spi 2·1 and -casein promoters upon receptor stimulation in a ligand specific manner. In contrast, only GHR1 but not GHR2 in seabream could trigger the c-fos promoter activity, indicating that the two GHR subtypes possess some differences in their signal transduction mechanisms. Also, the expression of GHR2 is significantly higher than GHR1 in many tissues of the seabream including the gonad, kidney, muscle, pituitary and spleen. In vivo hormone treatment data indicated that cortisol upregulated hepatic GHR1 expression in seabream but not GHR2, whereas testosterone decreased hepatic GHR2 expression but not GHR1. On the other hand, hepatic expression of both GHR1 and GHR2 in seabream was decreased by estradiol treatment.

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Effects of food deprivation on expression of growth hormone receptor and proximate composition in liver of black seabream Acanthopagrus schlegeli

Cited by 60 publications

References 44 publications

The Effect of Short-term Starvation on Some Physiological and Morphological Parameters in Juvenile Siberian Sturgeon, Acipenser Baerii (Actinopterygii: Acipenseriformes: Acipenseridae)

The Effect of Short-term Starvation on Some Physiological and Morphological Parameters in Juvenile Siberian Sturgeon, Acipenser Baerii (Actinopterygii: Acipenseriformes: Acipenseridae)

Coordinated regulation of the GH/IGF system genes during refeeding in rainbow trout (Oncorhynchus mykiss)

The co-existence of two growth hormone receptors in teleost fish and their differential signal transduction, tissue distribution and hormonal regulation of expression in seabream

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