Effects of general anaesthesia and ultrasonography‐guided interscalene block on pain and oxidative stress in shoulder arthroscopy: A randomised trial

Öksüz, Murat; Abitağaoğlu, Süheyla; Kaciroglu, Ahmet; Köksal, Ceren; Öztürk, Burak; Erel, Özcan; Senat, Almila; Arı, Dilek Erdoğan

doi:10.1111/ijcp.14948

Cited by 4 publications

(5 citation statements)

References 25 publications

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“…Oksuz et al compared oxidative stress parameters in patients who were given general anesthesia and those who received interscalene block during shoulder arthroscopy and found that postoperative thiol levels were lower and disulfide levels were higher in the general anesthesia group. Therefore, the authors concluded that general anesthesia increases oxidative stress, that this was directly proportional to VAS scores, and pain increases oxidative stress (24).…”

Section: Discussionmentioning

confidence: 99%

“…In the study by Oksuz et al, it was observed that MAP values were higher in the general anesthesia group compared to the interscalene block group only in the postoperative follow-up and was lower in all other times. This was thought to be due to the higher level of pain in the general anesthesia group (24). Major changes in blood pressure can affect oxidative stress parameters.…”

Section: Discussionmentioning

confidence: 99%

“…Turnike indirilmesi sonrası 5. (T2) ve 40. dakikalarda (T3) ve 24. saatte (T4) doğal tiyol, toplam tiyol, disülfit, disülfit/doğal tiyol oranı, disülfit/toplam tiyol oranı ve doğal tiyol/toplam tiyol oranı bakılmak üzere kan örnekleri toplandı.…”

Section: öZunclassified

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The Effect of Spinal and General Anesthesia on Thiol-Disulfide Balance During Ischemia/Reperfusion of the Leg in Patients Undergoing Knee Replacement Surgery

Simsek,

Aksoy,

Nurettin Manti

et al. 2023

JARSS

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Objective: Surgical trauma causes serious neuroendocrine and cytokine activity. In addition, the free oxygen radicals formed because of the ischemia/reperfusion injury resulting from applying and releasing the tourniquet (TQ) cause oxidative stress. Thiol and disulfide are among the new oxidative stress parameters used reliably in recent years. The aim of this study was to compare thiol-disulfide balance in general and spinal anesthesia, which are frequently used in total knee replacement (TKR) surgery. Methods: Fifty six patients aged 60-74 years scheduled to undergo TKR were randomly allocated to the general anesthesia (n=26) and spinal anesthesia (n=30) groups. The tourniquet (TQ) was applied for the TKR procedure after collecting a preanesthetic blood sample (T1). Blood samples were also collected at 5 minutes (T2) and 40 minutes (T3) after TQ release and at postoperative 24 hours (T4) to analyze native thiol, total thiol, disulfide, disulfide/native thiol ratio, disulfide/total thiol ratio, and native thiol/total thiol ratio. All patients had intravenous patient-controlled analgesia during the postoperative period. Mean arterial pressure, TQ times, and Visual Analogue Scale (VAS) scores were recorded. Decrease in thiol and increase in disulfide in the thiol-disulfide balance were recorded as oxidative stress indicators. Results: There was no difference between the groups in terms of VAS and analgesic consumption at the end of 24 hours. The general anesthesia group had higher native thiol, total thiol, and native thiol/total thiol ratio and lower disulfide, disulfide/native thiol ratio, and disulfide/total thiol ratio at all time points compared to the spinal anesthesia group. Conclusion: Assessment in terms of thiol-disulfide balance suggests that general anesthesia had a favorable effect on oxidative stress. Keywords: General anesthesia, oxidative stress, spinal anesthesia, thiol-disulfide, tourniquet time, visual analogue scale

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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The Effect of Spinal and General Anesthesia on Thiol-Disulfide Balance During Ischemia/Reperfusion of the Leg in Patients Undergoing Knee Replacement Surgery

Simsek,

Aksoy,

Nurettin Manti

et al. 2023

JARSS

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“…In this experiment, one-lung ventilation in thoracic surgery and other factors predisposed the lung to ischemia-reperfusion injury and consequently to oxidative stress, lung injury, and release of inflammatory factors [ 24 , 25 ]. Effective regional nerve block induced less oxidative stress during the postoperative period [ 26 ]. Some studies have explored the relationship between nerve block and inflammatory factors and found that nerve block blocking pain stimulation inhibited the increase of inflammatory factors in plasma [ 27 , 28 ].…”

Section: Discussionmentioning

confidence: 99%

Comparison of Rhomboid Intercostal Block, Erector Spinae Plane Block, and Serratus Plane Block on Analgesia for Video-Assisted Thoracic Surgery: A Prospective, Randomized, Controlled Trial

Zhang

Jiang

Deng

et al. 2022

International Journal of Clinical Practice

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Background. Thoracic surgery is one of the most painful surgical steps. An important tool for managing postoperative pain is effective postoperative analgesia. This research aimed at comparing the analgesic roles of three new fascial block techniques in the postoperative period after video-helped thoracoscopic operation (VATS). Methods. We randomly allocated ninety patients into three teams experiencing ultrasound-directed serratus plane block, erector spinae plane block, and the rhomboid intercostal block, respectively. 0.4% ropivacaine of 20 mL was received by all groups. Outcomes. At 0–12 hours, sufentanil consumption was significantly lower in the RIB (35.2 ± 3.3 mg) and ESP (35.4 ± 2.8 mg) groups than that in the SAB (43.3 ± 2.7 mg) group P < 0.001 , and no obvious diversity in sufentanil consumption was shown between the RIB and ESP groups P = 0.813 . At 12–24 hours, sufentanil consumption was greatly lower in the RIB and ESP groups than that in the SAB group P < 0.001 , and no great diversity in sufentanil consumption was found between the RIB and ESP groups P = 0.589 . No great diversity in sufentanil consumption was shown between the RIB (50.4 ± 1.4 mg), ESP (50.4 ± 1.5 mg), and SAB (51.0 ± 1.7 mg) groups at 24–48 hours P = 0.192 . At 6, 12, 18, and 24 hours, the postoperative dynamic NRS scores were significantly lower in the RIB and ESP groups than in the SAB group ( P < 0.05 for all contrasts). Nevertheless, no great diversity was observed in postoperative pain marks at 0.5, 1, 3, 6, 12, 18, 24, 36, and 48 hours after the surgery across the three groups. No statistical diversity was found in the postoperative NRS mark between groups RIB and ESP within 48 hours after surgery in case of active patients ( P < 0.05 for all contrasts). At 24 hours after surgery, a significant difference in IL-1β and IL-6 inflammatory factor concentrations was found between RIB and ESP compared with SAB block ( P < 0.05 for all contrasts). However, no great diversities were observed in IL-1β, and IL-6 inflammatory factor concentrations between RIB, ESP, and SAB at 24 hours preoperatively and at 48 hours postoperatively ( P < 0.05 for all comparisons). Conclusion. The dosage of sufentanil can be effectively reduced by ultrasound-directed rhomboid intercostal block and erector spinae plane block within 24 hours after VATS surgery, and pain can be relieved effectively within 24 hours by comparing with serratus plane block.

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“…A single bolus ISB can provide 8 hours of analgesic effect after an operation, and a continuous infusion reduces pain for up to 2 days postoperative [ 29 , 30 ]. The ISB induces less oxidative stress during surgery and can be helpful for perioperative hemodynamic stability [ 31 ]. Salviz et al [ 20 ] compared outpatient ARCR patients given a single bolus ISB, a continuous infusion ISB, or general anesthesia.…”

Section: Regional Blocksmentioning

confidence: 99%

Regional nerve blocks for relieving postoperative pain in arthroscopic rotator cuff repair

Kim

Hwang

2022

Clin Shoulder Elbow

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Rotator cuff tear is the most common cause of shoulder pain in middle-age and older people. Arthroscopic rotator cuff repair (ARCR) is the most common treatment method for rotator cuff tear. Early postoperative pain after ARCR is the primary concern for surgeons and patients and can affect postoperative rehabilitation, satisfaction, recovery, and hospital day. There are numerous methods for controlling postoperative pain including patient-controlled analgesia, opioid, interscalene block, and local anesthesia. Regional blocks including interscalene nerve block, suprascapular nerve block, and axillary nerve block have been successfully and commonly used. There is no difference between interscalene brachial plexus block (ISB) and suprascapular nerve block (SSNB) in pain control and opioid consumption. However, SSNB has fewer complications and can be more easily applied than ISB. Combination of ANB with SSNB has a stronger analgesic effect than SSNB alone. These regional blocks can be helpful for postoperative pain control within 48 hours after ARCR surgery.

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Effects of general anaesthesia and ultrasonography‐guided interscalene block on pain and oxidative stress in shoulder arthroscopy: A randomised trial

Cited by 4 publications

References 25 publications

The Effect of Spinal and General Anesthesia on Thiol-Disulfide Balance During Ischemia/Reperfusion of the Leg in Patients Undergoing Knee Replacement Surgery

The Effect of Spinal and General Anesthesia on Thiol-Disulfide Balance During Ischemia/Reperfusion of the Leg in Patients Undergoing Knee Replacement Surgery

Comparison of Rhomboid Intercostal Block, Erector Spinae Plane Block, and Serratus Plane Block on Analgesia for Video-Assisted Thoracic Surgery: A Prospective, Randomized, Controlled Trial

Regional nerve blocks for relieving postoperative pain in arthroscopic rotator cuff repair

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