Effects of ginger along with exercise training on serum levels of ALT and AST liver enzymes and malondialdehyde and the activity of liver tissue superoxide dismutase in male Wistar rats

Ghasemnian, Aghaali; Iddehloei, Zeinab; Rahmani, Ahmad; Usefpour, Mozhgan

doi:10.34172/jsums.2020.11

Cited by 2 publications

(1 citation statement)

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“…The most sensitive and profitable diagnostic enzymes of the liver status are aminotransferases including aspartate aminotransferase (AST) and alanine aminotransferase (ALT) Generally, certain amounts of these enzymes are produced by liver cells, yet after liver damage, the liver cells increase the secretion of the enzymes and their plasma levels, (Terohid et al, 2015).The incidence of oxidative stress in the body has other negative effects, such as muscle fatigue, early restlessness impaired, decreased immune function, and muscle oxidation (Bloomer and Goldfarb, 2004).The results showed that 60 days of training protocol had slight alteration effect on serum levels of ALT and AST on +ve control and corn silk feeding groups exposed to exhaustive test. The lack of alteration is inconsistent with the findings of Kim et al,(2007) and Ghasemnian et al,(2020).Acute strenuous exercise induces oxidative stress and/or tissue damage in several tissues including skeletal muscle, liver, and kidney (Suzuki et al, 2003, Aoi et al .,2004,Suzuki ,2018. Davies et al, 1982 reported that exhaustive exercise increases reactive oxygen species (ROS) generation and induces tissue damage in liver and skeletal muscle.…”

Section: Discussionmentioning

confidence: 96%

Comparative study among Corn silk, Pumpkin Seeds, and Creatine to test the efficiency of physical activity in rat

Haggag

Rabeh

Mohammed

2020

Egyptian Journal of Nutrition and Health

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The present study was conducted to investigate the effect of corn silk,pumpkin seeds and creatine supplementation on kidney function, liver function, glucose, creatine kinase and lactate dehydrogenase in adult male rats subjeced to exercise training. Fifty male albino rats, were fed on basal diet for one week for adaptation. During the adaptive week all rats (except negative control group) were exposed to day after day forced treadmill running exercise for 10 min. Rats were divided into two main groups, the first main group (n=10 rats) was fed on basal diet only and served as negative control group. The second main group (exercised rats) were divided into 4 subgroups (10 rats each) as follows:-Subgroup 1: were fed on basal diet and had run for 10, 15, 20 and 25minutes(15 days for each time periodrespectively) to complete 60 days, and served as positive control group. And the rest of Subgroups (2-4) were fed on basal diet supplemented with 4% corn silk powder, 4% pumpkin seeds powder and 4% creatine powder, respectively as the same exercise of positive control subgroup. At the end of the experimental period (60 day), each subgroup were exposed to the exhausting treadmill test and the run time was recorded, then all experimental rats were scarified.From the obtained results we concluded that pumpkin seed have bioactive compounds that elevate the exercise performance ,and prolong the exhaustive time ,corn silk have a good effect in glucose level by increasing insulin level and recovering injured beta cells, and not via increasing glycogen or inhibiting gluconeogenesis ,although creatine recorded the largest glycogen quantity in gastrocnemius muscles among supplemented groups, but it caused an elevation of ammonia,AST ,and uric acid levels when exposed to exhaustive time test . So future studies are recommended to clarify creatine benefit in exercise field .The study advised to consume corn silk and pumpkin seed to prolong exercise time and accelerate recovery from exercise training.

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