The increased demand for construction materials and environmental hazards due to industrial-associated wastes provide scope for sustainable solution pathways. Hence, this study focused on determining the possibility of using waste glass powder as a replacement for clay in burnt clay bricks for improved mechanical performance and durability. According to the tests performed under ASTM, the bricks were executed for compressive strength, modulus of rupture, water absorption, apparent porosity, efflorescence resistance, and ultrasonic pulse velocity for various WGP substitutions starting from 0% and ending with 25%. The results of the tests indicated that samples with up to 20% recorded the highest increase in compressive strength and modulus of rupture of approximately 25% and 41%, respectively. Excellent results proved that WGP improved structure integrity and durability, enhancing their potential as a waste management solution as an eco-friendly additive that reduces dependence on natural clay. This study concluded that the WGP-modified bricks can be a valid replacement for sustainable construction applications. To enhance the suitability of WGP for sustainable construction, more studies must be carried out on optimizing firing parameters, long-term durability evaluation, and scaling up production processes to facilitate broader industrial adoption.