Effects of glucocorticoid on the ultrastructure of the mouse parathyroid gland.

Effects of Ovariectomy on the Ultrastructure of the Parathyroid Gland of the Golden Hamster

“…The area occupied by lipid droplets appears-to be increased, and the number of secretory granules in the peripheral cytoplasm and large vacuolar bodies appears to be decreased compared to those of the control ani mal. These findings are fairly consistent with the obser vations of a decrease in functional activity of the para thyroid gland [Stoeckel and Porte, 1966;Isono and Shoumura-Sakurai, 1973;Young et al, 1973;Roth and Schiller, 1976;Isono et al, 1977Isono et al, , 1978Isono et al, , 1981Isono et al, , 1982Isono et al, , 1983Hayashi et al, 1981]. Therefore, it is possi ble to speculate that the synthesis and release of para thyroid hormone may be suppressed in many chief cells of the ovariectomized golden hamsters.…”

“…The presence of coated vesicles in the parathyroid gland has been described in frogs [Rogers, 1965], newts [Setoguti et al, 1970;Shoumura, 1973], lizards |Isono et al, 1979a], birds [Shoumura, 1974], chicks [Chan, 1977], mice [Isono et al, 1979b[Isono et al, , 1983 and rabbits Isono et al, 1982]. In the present study, small coated vesicles of 70 nm in diameter are also observed in the region of the Golgi complex.…”

“…1982Isono et al, , 1983Hayashi et al, 1980Hayashi et al, , 1981Isono and Shoumura, 1980;Setoguti et al, 1981]. Large secretory granules of 400-600 nm in diameter are also present in the chief cells of the control and ovariectomized golden hamsters.…”

The Effect of Magnesium on the Fine Structure of the Golden Hamster Parathyroid Gland in Vivo and in Vitro

“…These findings on the Golgi apparatus and cisternae of the rough endoplasmic reticulum in the in vivo and in vitro study are fairly consistent with the observations which indicate a decrease in functional activity of the parathyroid gland (Isono et aL, 1980(Isono et aL, , 1982(Isono et aL, , 1983(Isono et aL, , 1985 Therefore, it is suggested that Mg acts as a suppressive factor for the synthesis of PTH in the short term, and directly affects the chief cell of the hamster parathyroid gland. …”

Effects of Starvation on the Water-Clear Cell in the Golden Hamster Parathyroid Gland

“…It has been described that the hypoactive chief cells showed an increase in lipid droplets (Isono et al, 1980(Isono et al, ,1982(Isono et al, ,1983Hayashi et al, 1981;Shoumura et al, 1988). Furthermore, it has been demonstrated that the chief cells of the parathyroid gland in the starved mice showed a decrease in the Golgi complexes and cisternae of the granular endoplasmic reticulum (Isono et at., 1985).…”