Effects of glucocorticoids on growth and bone mineralization

Donatti, Teresinha Lermen; Koch, Vera H.; Takayama, Liliam; Pereira, Rosa Maria Rodrigues

doi:10.2223/jped.2052

Cited by 20 publications

(15 citation statements)

References 63 publications

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“…Motivo pelo qual os de exercício de força devem fazer parte da prescrição para idosos, reforçando estudos prévios. 18,19 Como esperado, as idosas que faziam hidroginástica apresentavam melhor capacidade funcional em comparação com as idosas sedentária, por este motivo medidas devem ser tomadas para incentivar cada vez mais idosos a envolverem-se em programas regulares de exercício físico, como a hidroginástica, e neste sentido um sinal de alerta precisa ser ligado, pois evidências científicas demonstram que idosos apresentam risco aumentado para desenvolver hipertensão, síndrome metabólica, osteoporose, dislipidemia 20,21 e o exercício 19 físico regular pode ser um importante coadjuvante na manutenção da capacidade funcional e saúde de idosos.…”

Section: Discussionunclassified

Papel da hidroginástica na capacidade funcional de idosos - Role of hydrogymnastic in the functional capacity of elderly

Oliveira‐Silva¹,

Arcanjo²

2017

RESU

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ResumoObjetivo: Apresentar a influência de um programa de hidroginástica na capacidade funcional de idosas. Métodos: Com uma amostra de 60 idosas com média de idade de 65,9±3,2 anos, subdivididas em dois grupos: 30 praticantes de hidroginástica e 30 sedentárias. Para este estudo foi aplicado à bateria de testes de Rikli e Jones (2008), que é constituída por um conjunto de testes que permitem avaliar a capacidade funcional de idosos. Utilizou-se o software SPSS for Windows versão 22.0, e o nível de significância adotado foi de p ≤ 0,05. Resultados: Ficou evidenciado que as idosas que frequentavam as aulas de hidroginástica a mais de 6 meses apresentaram níveis de capacidade funcional superiores em todos os testes da bateria em comparação com as idosas sedentárias (p=0.01). Conclusões: Um programa de hidroginástica de mais de seis meses influencia positivamente na capacidade funcional de idosas. Contudo recomenda-se a inclusão de exercícios de força para minimizar as perdas deste componente a medida que a idade avança. Palavras-chave:Idosos. Capacidade. Hidro. AbstractObjective: To present the influence of a hydrogymnastic (water aerobics) program on the functional capacity of elderly women. Methods: With a sample of 60 elderly women with mean age of 65.9 ± 3.2 years, subdivided into two groups: 30 hydrogymnastic practitioners and 30 sedentary. For this study was applied the test of Rikli and Jones (2008), which consists of a set of tests that allow to evaluate the functional capacity of the elderly. The software SPSS for Windows version 22.0 was used, and the significance level adopted was p ≤ 0.05. Results: It was evidenced that the elderly women attending hydrogymnastic classes over 6 months had higher levels of functional capacity in all battery tests compared to sedentary women (p=0.01). Conclusions: An program of hydrogymnastic in more than six months has positively influences the functional capacity of the elderly. However, it is recommended to include strength exercises to minimize the losses of this component as the age advances.

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Section: Discussionunclassified

Papel da hidroginástica na capacidade funcional de idosos - Role of hydrogymnastic in the functional capacity of elderly

Oliveira‐Silva¹,

Arcanjo²

2017

RESU

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“…1,2 Although the effects of systemic glucocorticoid therapy have been reported extensively, 3 little is known about the systemic effects of local glucocorticoid injections. Exogenous glucocorticoids can suppress the hypothalamic-pituitary-adrenal axis (HPAA), which is problematic because patients are vulnerable to adrenal insufficiency during times of stress such as illness.…”

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confidence: 99%

Changes in Blood Glucose and Cortisol Levels After Epidural or Shoulder Intra-articular Glucocorticoid Injections in Diabetic or Nondiabetic Patients

Moon

Choi²,

Lee³

et al. 2014

American Journal of Physical Medicine &Amp; Rehabilitation

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“…After maturation of ECM, there is an expression of ALP enzymes and several proteins, like osteocalcin, osteopontin, and bone sialoproteins. Overall, the bone mineralization is dependent on a tight local balance between extracellular levels of inorganic phosphate (Pi) and inorganic pyrophosphate (PPi) which is regulated by different ALP enzymes [46]. The bone mineralization in MG-63 cells is shown in Figure 4.…”

Section: Assessment Of Bone Mineralization By Alizarin Red S (Ars) Stmentioning

confidence: 99%

Evaluation of Biofield Energy Treated Vitamin D<sub>3</sub> on Bone Health Parameters in Human Bone Osteosarcoma Cells (MG-63)

Koster¹,

Trivedi²,

Branton³

et al. 2018

BMB

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The study was aimed to evaluate the effect of Consciousness Energy Healing based vitamin D 3 and DMEM medium on bone health parameters. The test items, were divided into two parts. One part of each sample received the Consciousness Energy Healing Treatment by Dezi Ann Koster and those samples were labeled as the Biofield Energy Treated (BT) samples, while the other parts of each sample were denoted as the untreated test items (UT). Different parameters were performed for the evaluation of bone health like ALP, collagen, and bone mineralization in human bone osteosarcoma cells (MG-63). The cell viability (MTT) data showed the test samples were found as safe in the tested concentrations. The level of ALP was significantly increased by 431.44% and 436.87% in the BT-DMEM + UT-Test item and BT-DMEM + BT-Test item, respectively at 1 µg/mL compared to the UT-DMEM + UT-Test item group. Further, the ALP level was significantly elevated by 163.34%, 44.91%, and 57.67% in the UT-DMEM + BT-Test item, BT-DMEM + UT-Test item, and BT-DMEM + BT-Test item groups, respectively at 50 µg/mL compared to the untreated. Collagen was significantly increased by 56.58%, 84.95%, and 43.27% in the UT-DMEM + BT-Test item, BT-DMEM + UT-Test item, and BT-DMEM + BT-Test item, respectively at 0.1 µg/mL compared to the untreated. Further, the collagen level was significantly increased by 21.27%, 47.26%, and 63.1% in the UT-DMEM + BT-Test item, BT-DMEM + UT-Test item, and BT-DMEM + BT-Test item groups, respectively at 50 µg/mL compared to the untreated. Besides, the percent of bone mineralization was distinctly increased by 41.87% and 91.87% at 1 µg/mL in the BT-DMEM + UT-Test item and BT-DMEM + BT-Test item groups, respectively while, increased by 72.66% and 186.68% at 50 µg/mL in the UT-DMEM + BT-Test item and BT-DMEM + BT-Test item groups, respectively compared to the untreated. The percent of bone mineralization was distinctly increased by 101.21%, 57.76%, and 125.53% in the UT-DMEM + BT-Test item, BT-DMEM + UT-Test item, and BT-DMEM + BT-Test item, respectively at 10 µg/mL compared to the untreated. Altogether, the Biofield Energy Treated vitamin D 3 was significantly improved the bone health parameters and it could be an excellent alternative nutraceutical supplement against various bone-related disorders including osteoporosis, low bone density, osteogenesis imperfecta, Paget's disease, rickets, osteomalacia, deformed bones, autoimmune and inflammatory diseases, stress management and prevention, and anti-aging by improving overall health.

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Effects of glucocorticoids on growth and bone mineralization

Cited by 20 publications

References 63 publications

Papel da hidroginástica na capacidade funcional de idosos - Role of hydrogymnastic in the functional capacity of elderly

Papel da hidroginástica na capacidade funcional de idosos - Role of hydrogymnastic in the functional capacity of elderly

Changes in Blood Glucose and Cortisol Levels After Epidural or Shoulder Intra-articular Glucocorticoid Injections in Diabetic or Nondiabetic Patients

Evaluation of Biofield Energy Treated Vitamin D<sub>3</sub> on Bone Health Parameters in Human Bone Osteosarcoma Cells (MG-63)

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Effects of glucocorticoids on growth and bone mineralization

Cited by 20 publications

References 63 publications

Papel da hidroginástica na capacidade funcional de idosos - Role of hydrogymnastic in the functional capacity of elderly

Papel da hidroginástica na capacidade funcional de idosos - Role of hydrogymnastic in the functional capacity of elderly

Changes in Blood Glucose and Cortisol Levels After Epidural or Shoulder Intra-articular Glucocorticoid Injections in Diabetic or Nondiabetic Patients

Evaluation of Biofield Energy Treated Vitamin D&lt;sub&gt;3&lt;/sub&gt; on Bone Health Parameters in Human Bone Osteosarcoma Cells (MG-63)

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Evaluation of Biofield Energy Treated Vitamin D<sub>3</sub> on Bone Health Parameters in Human Bone Osteosarcoma Cells (MG-63)