Effects of glycine–metal compounds on Ascaridia galli-infected chickens expressed by a kinetic model

Abstract

The biogenic elements zinc, manganese and cobalt are essential for metabolic processes in animals. Compounds of nGly.Me2+A. mH2O (Me2+=Zn2+, Mn2+, Co2+; A=Cl(-), SO4(2-), n=1, 2; m=2, 5), as supplements in the diet, were used separately on different experimental groups of male Hisex chickens to correct the mineral deficiency caused by Ascaridia galli infections. An amelioration of body weight gain, reduction of mortality and restoration of trace element levels were estimated in infected chickens. A mathematical model has been proposed for A. galli population kinetics in chickens, taking into account the stimulating effect of these elements on the nematodes. The model parameters are considered as phenomenological constants of the host-parasite system. An agreement with experimental data is observed using, for the parameters psi, alpha, micro and micros, values equal to those calculated in previously investigated A. galli-chicken systems. For parameter nu (immunological constant) the same value was obtained as in a previous experiment with high infection. This model is likely to be suitable for a range of host-nematode systems, including varying degrees of infection and treatment with different trace elements.

Effect of selenium and Ascaridia galli infection on antioxidant biomarkers in broiler chickens: a mathematical model for parasite reduction and host growth

“…But Se supplementation improves the immunity response of the host and for this reason we should expect a greater nematode reduction in group 4. The present value of n is almost twice higher than n in our previous studies with Leghorn (Hisex breed) chickens (Gabrashanska et al, , 2004a. The enhanced concentration of Se in ascaridiae may be due to the compounds in their organism, which activate some enzyme systems during oxidation -reduction processes, especially glutathione peroxidase containing Se in its active centre.…”

Administration of Zn-Co-Mn basic salt to chickens with ascaridiosis

“…In our previous studies (Gabrashanska et al , 2004, in which the same doses of 1,450 embryonated A. galli eggs were used, a repeated value of m=0.026 day -1 was obtained using the mathematical model, and in the case of infection with 450 embryonated A. galli eggs (Gabrashanska et al 1999a), a value of m=0.0167 day -1 was calculated. The difference between the values of the kinetic parameter m is likely to be due to the different degrees of infection: a higher infection stimulates a stronger immune response.…”

Characterization and Thermal Behavior of the Iron Dietary Supplement Ferrous Glycine Sulfate Pentahydrate

“…Glycine based metal(II) salts with cobalt, zinc, and manganese show positive effects in correcting mineral deficiency in animals . The iron(II) based salt is used as a therapeutic agent to prevent or treat iron deficiency anaemia in infants, or in lactating and pregnant women.…”