Effects of Helicobacter pylori Eradication on Gastroesophageal Reflux Disease

Qian, Bingbing; Ma, Shijie; Li, Shang; Qian, Juan; Zhang, Guoxin

doi:10.1111/j.1523-5378.2011.00846.x

Cited by 64 publications

(39 citation statements)

References 24 publications

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“…However, the short follow-up after eradication may account for the discrepancy between studies. HP eradication does not seem to exacerbate the disease in patients with GORD, thus HP infection in GORD patients may be eradicated (17). Further supporting HP eradication in GORD patients is the need for long-term proton pump inhibitor (PPI) therapy that seems to be associated with an increased risk of developing gastric precancerous conditions, such as corpus atrophic gastritis (18,19).…”

Section: Hp and Gastro-oesophageal Reflux Diseasementioning

confidence: 98%

Guidelines for the management of Helicobacter pylori infection in Italy: The III Working Group Consensus Report 2015

Zagari

Romano

Ojetti

et al. 2015

Digestive and Liver Disease

118

149

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Knowledge on the role of Helicobacter pylori (HP) infection is continually evolving, and treatment is becoming more challenging due to increasing bacterial resistance. Since the management of HP infection is changing, an update of the national Italian guidelines delivered in 2007 was needed. In the III Working Group Consensus Report 2015, a panel of 17 experts from several Italian regions reviewed current evidence on different topics relating to HP infection. Four working groups examined the following topics: (1) "open questions" on HP diagnosis and treatment (focusing on dyspepsia, gastro-oesophageal reflux disease, non-steroidal anti-inflammatory drugs or aspirin use and extra-gastric diseases); (2) non-invasive and invasive diagnostic tests; (3) treatment of HP infection; (4) role of HP in the prevention of gastric cancer. Statements and recommendations were discussed and a consensus reached in a final plenary session held in February 2015 in Bologna. Recommendations are based on the best current evidence to help physicians manage HP infection in Italy. The guidelines have been endorsed by the Italian Society of Gastroenterology and the Italian Society of Digestive Endoscopy.

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Section: Hp and Gastro-oesophageal Reflux Diseasementioning

confidence: 98%

Guidelines for the management of Helicobacter pylori infection in Italy: The III Working Group Consensus Report 2015

Zagari

Romano

Ojetti

et al. 2015

Digestive and Liver Disease

118

149

View full text Add to dashboard Cite

show abstract

“…Fetal considerations include the preservation of adequate maternal oxygenation and blood pressure to allow optimal placental perfusion. Only a few studies have been published on the safety of endoscopy during pregnancy but all showed that gastroscopy and colonoscopy are not associated with adverse outcomes 46 49 133. Where therapeutic intervention is necessary, endoscopy offers a relatively safe alternative to radiological or surgical intervention 34 35 134–138…”

Section: Liver Disease During Pregnancymentioning

confidence: 99%

Management of gastrointestinal and liver diseases during pregnancy

Woude

Metselaar

Danese

2014

Gut

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In the majority of patients with chronic gastrointestinal and liver diseases, maintenance therapy is required during pregnancy to control the disease, and disease follow-up or disease control might necessitate endoscopy. Evidence on the safety of drugs and imaging techniques during pregnancy is scarce and sometimes difficult to interpret. In this review we summarise existing literature with the aim of optimising counselling of patients with common chronic gastrointestinal and liver diseases who want to conceive.

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“…By the way, other studies evaluating the same relation actually produced inconsistent results [75]. A systematic review by Qian et al [76] was aimed to evaluate whether the eradication of HP would worsen or improve GERD, both from the clinical (heartburn, acid regurgitation) and endoscopical (erosive esophagitis) point of view. The 11 articles included in this met-analysis showed no significant difference between patients with HP eradicated and those with persistent infection.…”

Section: H Pylori Infection and Diseases Of The Upper Gastrointesmentioning

confidence: 99%

Helicobacter pyloriEradication Therapy: Current Availabilities

Gasparetto

Pescarin

Guariso

2012

ISRN Gastroenterology

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Background. Though Helicobacter pylori (HP) infections have progressively declined throughout most of the industrialized countries, a gradual increase in failure of HP eradication treatments is observed. Aim. To critically review evidence on the efficacy of the therapeutic availabilities for HP eradication, as yet. Methods. A selection of Clinical Trials, Systematic Reviews and Meta-analyses within the time period 2010–2012, was performed through a Medline search. Previous references were included when basically supporting the first selection. Results. An increasing rise in HP resistance rates for antimicrobial agents is currently observed. Further causes of HP treatment failure include polymorphisms of the CYP 2C19, an increased body mass index (BMI), smoking, poor compliance and re-infections. Alternative recent approaches to standard triple therapy have been attempted to increase the eradication rate, including bismuth-containing quadruple therapy, non-bismuth containing quadruple therapy, sequential therapy and levofloxacin-containing regimens. Conclusions. The main current aims should be the maintenance of a high eradication rate (>85%) of HP and the prevention of any increase in antimicrobial resistance. In the next future, the perspective of a tailored therapy could optimize eradication regimens within the different countries.

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Effects of Helicobacter pylori Eradication on Gastroesophageal Reflux Disease

Abstract: H. pylori eradication does not aggravate the clinical outcomes in terms of short-term and long-term posteradication occurrence of GERD. There is no association between H. pylori eradication and the development of GERD in the patients with different diseases, even those with GERD.

Cited by 64 publications

References 24 publications

Guidelines for the management of Helicobacter pylori infection in Italy: The III Working Group Consensus Report 2015

Guidelines for the management of Helicobacter pylori infection in Italy: The III Working Group Consensus Report 2015

Management of gastrointestinal and liver diseases during pregnancy

Helicobacter pyloriEradication Therapy: Current Availabilities

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