Dam Foundation; The Liaison Committee for education, research and innovation in Central Norway Although aerobic interval training (AIT) is recognized to attenuate the risk of cardiovascular disease (CVD) and premature mortality, it appears that it rarely arrives at patients' doorsteps. Thus, this study investigated 1-year effects and feasibility of AIT delivered with adherence support in collaborative care of outpatients with schizophrenia. Forty-eight outpatients (28 men, 35 [31-38] (mean [95% confidence intervals]) years; 20 women, 36 [30-41] years) with schizophrenia spectrum disorders (ICD-10) were randomized to either a collaborative care group provided with municipal transportation service and training supervision (walking/running 4 × 4 minutes at ~90% of peak heart rate; HR peak) 2 d wk −1 at the clinic (TG) or a control group (CG) given 2 introductory AIT sessions and advised to continue training. Directly assessed peak oxygen uptake (VO 2peak) increased in the TG after 3 months (2.3 [0.6-4.4] mL kg −1 min −1 , Cohen's d = 0.33[−4.63 to 4.30], P = 0.04), 6 months (2.7 [0.5-4.8] mL kg −1 min −1 , Cohen's d = 0.42[−4.73 to 4.11], P = 0.02) and 1 year (4.6 [2.3-6.8] mL kg −1 min −1 , Cohen's d = 0.70[−4.31 to 4.10], P < 0.001) compared to the CG. One-year cardiac effects revealed higher HR peak (7 [2-11] b min −1 , Cohen's d = 0.34[−8.48 to 8.65], P = 0.01), while peak stroke volume tended to be higher (0.9 [−0.2 to 2.0] mL b −1 , Cohen's d = 0.35[−1.62 to 2.