Effects of High-Intensity Interval Training Protocols on Liver Enzymes and Wellness in Women

Rengers, Timothy A.; Orr, Samantha C.; Marks, Charles; Hew‐Butler, Tamara; Choi, Myung Dong; Butcher, Scotty; Drignei, Dorin; Brown, Elise C.

doi:10.1155/2021/5554597

Cited by 3 publications

(2 citation statements)

References 46 publications

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“…This suggests that dancing exercise may be an effective treatment to reduce the levels of these enzymes in healthy individuals compared to the pre-dancing group. This result indicates that dancing can be beneficial in decreasing ALT and AST levels and reducing the potential risk of liver injury [35][36][37]. ALP is an enzyme produced by the liver, bones, and kidneys and is often used to monitor bone growth and diagnose osteoporosis [38].…”

Section: Discussionmentioning

confidence: 99%

Dancing Exercise Enhances Metabolic Functions via Hypercortisolism-Mediated Inhibition of Inflammatory Cytokines in Healthy Adult Volunteers

Arientare Rume,

Mega Obukohwo,

Ejiro Ohwin

et al. 2024

OBM Integr Complement Med

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Regular physical activity has been proven to improve metabolism, slow aging, and decrease the likelihood of various health conditions such as obesity, type 2 diabetes, and cardiovascular disorders. Hence, dancing was evaluated for its effects on cardiovascular, liver enzymes, and biochemical markers among healthy adults. Forty (40) healthy adults (20-40 years old) were chosen for the study, with an average age calculated. Those with certain health conditions or habits were not allowed to participate. Twenty (20) men and 20 women were chosen for the study, which involved dancing for 15 minutes a day, five days a week, for four weeks. Pre- and post-dancing groups were compared to measure any changes. Results indicated positive effects on health and well-being. The two groups were compared to analyze changes to cardiovascular, liver enzymes, and lipid profiles over a 4-week dance intervention. Both groups received assessments before and after the program, with the initial assessment taking place at 0 weeks and a follow-up at 4 weeks. This study found that a 4-week period of dancing exercise improved cardiovascular and lipid profiles (p < 0.05) in both genders. These favorable impacts were reflected in lower systolic and diastolic blood pressure, decreased total cholesterol and triglycerides, and lowered LDL with corresponding increases in HDL. This study found that participating in a tailored dance exercise program decreased glucose, insulin, and HOMA index levels compared to pre-exercise levels. Additionally, levels of ALT, AST, and GGT dropped considerably, while ALP and LDH also decreased. Kidney function, including aminotransferase, creatinine, and uric acid, was also reduced after 24 hours of post-dancing exercise. Twenty-four hours of Post-dancing exercise was found to decrease serum IL-6, CRP, and stress hormones (epinephrine and cortisol) levels as well as increased IL-10 levels in healthy adults (P < 0.05). Dancing could be demonstrated to be a practical non-medicinal approach to help prevent metabolic syndrome and reduce inflammation through increased cortisol production in healthy adults.

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Section: Discussionmentioning

confidence: 99%

Dancing Exercise Enhances Metabolic Functions via Hypercortisolism-Mediated Inhibition of Inflammatory Cytokines in Healthy Adult Volunteers

Arientare Rume,

Mega Obukohwo,

Ejiro Ohwin

et al. 2024

OBM Integr Complement Med

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“…Moreover, football players may be at an increased risk for liver function abnormalities due to the high levels of oxidative stress and inflammation associated with intense physical activity. For instance, a study by Ekun et al 12 and Rengers et al 13 found that football players had significantly higher levels of liver enzymes.…”

Section: Introductionmentioning

confidence: 99%

Effects of an aerobic training program on liver functions in male athletes: a randomized controlled trial

Bari,

MahmoodAlobaidi,

Ansari

et al. 2023

Sci Rep

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The optimal functioning of the liver is essential for athletic performance. It is necessary to maintain the liver’s enzymes at an optimal level so that liver cells can be protected from inflammation or damage. This study investigated the effects of a 12-week aerobic exercise program on the liver function of adult athletes. A pretest–posttest experimental design was used. A total of thirty healthy male athletes (football players) aged 21 to 24 years were recruited for this study and randomly and equally divided into the experimental group (EG) and control group (CG). The CG did not participate in any special activities. The EG performed an aerobic training program consisting of several exercises for 12 weeks. Evaluation of all participants in both groups was carried out before and after the intervention by measuring the blood levels of Alkaline phosphate, AST/SGOT, ALT/SGPT, Bilirubin Total/indirect/direct, Albumin, Globulin, and Total protein using the standard methods by collecting blood samples. There was a significant decrease (p < 0.05) in Bilirubin and globulin levels in the EG after 12 weeks of aerobic training sessions. However, there was no significant difference in alkaline phosphate, AST/SGOT, ALT/SGPT Total protein, and Albumin (p > 0.05) between both groups post-treatment. The 12 weeks of aerobic training used in the study can potentially improve the liver function of adult athletes.

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High-Intensity Interval Training Reduces Liver Enzyme Levels and Improves MASLD-Related Biomarkers in Overweight/Obese Girls

Abassi,

Ouerghi,

Hammami

et al. 2025

Nutrients

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Background/Objectives: Despite the abundant body of evidence linking high-intensity interval training (HIIT) to cardiometabolic markers, little is known about how HIIT affects liver enzymes, particularly in obese adolescents. This study aimed to investigate the effects of HIIT on metabolic dysfunction-associated steatotic liver disease (MASLD)-related biomarkers in overweight/obese adolescent girls. Methods: Thirty-three overweight/obese adolescent girls (age, 17.0 ± 1.15 yr.; body mass index, 33.3 ± 4.77 kg/m2) were randomly assigned to HIIT (n = 17) or control (n = 16) groups. The HIIT group participated in a nine-week HIIT program (three times weekly) without caloric restriction. Maximal aerobic speed, body composition indexes, blood pressure, MASLD-related biomarkers [liver enzymes (alanine aminotransferase (ALT) and aspartate aminotransferase (AST)), plasma lipids, uric acid, platelet count, and homeostasis model assessment index for insulin-resistance (HOMA-IR)] were examined at baseline and after the intervention. Results: Significant “time × group” interactions were found for body composition indexes, systolic blood pressure, maximal aerobic speed, liver enzymes ALT and AST, plasma lipids, glucose, and HOMA-IR. The HIIT program resulted in an increase in maximal aerobic speed (p = 0.035) and a decrease in body composition and plasma lipids (p < 0.01), systolic blood pressure (p = 0.011), ALT (p = 0.013), AST (p = 0.012), and HOMA-IR (p = 0.01), but no significant changes in uric acid and platelet count. None of these markers changed in the control group. Conclusions: HIIT resulted in an improvement in MASLD-related biomarkers. HIIT could be an effective exercise therapy to prevent and reverse MASLD in adolescents with obesity.

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Effects of High-Intensity Interval Training Protocols on Liver Enzymes and Wellness in Women

Cited by 3 publications

References 46 publications

Dancing Exercise Enhances Metabolic Functions via Hypercortisolism-Mediated Inhibition of Inflammatory Cytokines in Healthy Adult Volunteers

Dancing Exercise Enhances Metabolic Functions via Hypercortisolism-Mediated Inhibition of Inflammatory Cytokines in Healthy Adult Volunteers

Effects of an aerobic training program on liver functions in male athletes: a randomized controlled trial

High-Intensity Interval Training Reduces Liver Enzyme Levels and Improves MASLD-Related Biomarkers in Overweight/Obese Girls

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