Effects of High Levels of Copper and Chlortetracycline on Performance of Pigs

Bunch, R. J.; Speer, V. C.; Hays, V. W.; McCall, John T.

doi:10.2527/jas1963.22156x

Cited by 30 publications

(20 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Liver iron levels were decreased approximately 50% by the addition of 250 ppm copper to the diet. Similar results were reported by Corzo (1972) and Bunch et al (1963Bunch et al ( , 1965. However, feeding sulfide as FeS in combination with copper prevented the decrease in liver iron caused by feeding high levels of dietary copper.…”

Section: Discussionsupporting

confidence: 89%

Effects of Copper Sulfate and Ferrous Sulfide on Performance and Liver Copper and Iron Stores of Pigs

Tj¹,

Vw²,

Gl³

1979

Journal of Animal Science

Self Cite

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 89%

Effects of Copper Sulfate and Ferrous Sulfide on Performance and Liver Copper and Iron Stores of Pigs

Tj¹,

Vw²,

Gl³

1979

Journal of Animal Science

Self Cite

View full text Add to dashboard Cite

“…Swine fed diets marginal in zinc and iron tolerate considerably less copper than those fed diets with greater amounts of these elements (Bunch et al, 1963). We therefore conducted Experiment 6 to determine whether the zinc and iron status of the purified diet was the cause of the marked growth depression with excess copper.…”

Section: Discussionmentioning

confidence: 99%

Effect of High-Level Copper Feeding on the Sulfur Amino Acid Need of Chicks Fed Corn-Soybean Meal and Purified Crystalline Amino Acid Diets

Robbins

Baker

1980

Poultry Science

View full text Add to dashboard Cite

Supplementation of a corn-soybean meal diet with .05% methionine maximized gain and feed efficiency of three-week-old chicks fed copper at either 0 or 250 mg/kg. With copper present at 500 mg/kg, the supplemental methionine requirement was in excess of .10%. Liver copper stores of chicks fed copper at 250 mg/kg declined linearly as supplemental methionine level increased, but methionine level had no effect on liver copper when chicks were fed 500 mg/kg copper. Liver copper accumulation did not occur in chicks fed 250 mg/kg copper when supplemental sulfur was provided as a combination of .05% methionine and 1800 mg/kg sulfide. Irrespective of methionine level, sulfide addition reduced liver copper by one-half in birds fed 500 mg/kg copper. Chicks fed the purified diet were appreciably more susceptible to copper toxicity than those fed the corn-soybean meal diet. Chicks fed the purified diet without supplemental copper required .52% sulfur amino acids (SAA). Chicks fed copper at 250 and 500 mg/kg required .65 and .70 SAA, respectively, although gain and feed efficiency were still depressed when compared with the performance of the control birds. Higher levels of methionine failed to restore growth rates to those achieved with birds fed no supplemental copper. Supplementing the copper-containing diets with up to 1.6% cystine improved performance some but failed to completely overcome the growth depressing effect of copper at 500 mg/kg. Results of additional studies indicated that the purified diet containing .70% SAA and 500 mg/kg copper was nutritionally adequate and that the marked toxicity of copper when fed in the purified diet was due to the chemical nature of the diet rather than to any specific copper-induced nutritional deficiencies.

show abstract

“…The sulfate salt of Cu is the most common source used in feeds for growth promotion. In studies with growing-finishing swine (Bunch et al, 1961(Bunch et al, , 1963, the oxide form of Cu was reported to be nearly as effective as the sulfate form, yet liver Cu levels were not elevated in their pigs when CuO was fed. However, in studies at our station, the feeding of high levels of Cu in the sulfide form neither enhanced growth rate nor did it influence liver Cu stores (Cromwell et al, 1978).…”

Section: Introductionmentioning

confidence: 99%

Effects of Source and Level of Copper on Performance and Liver Copper Stores in Weanling Pigs

Cromwell

Stahly

Monegue

1989

Journal of Animal Science

144

View full text Add to dashboard Cite

Five 28- to 33-d experiments involving 460 crossbred pigs weaned at 28 +/- 2 d of age (initial weight, 6.7 to 8.1 kg) were conducted to determine the effects of feeding high dietary levels of Cu sulfate (CuSO4) or Cu oxide (CuO) on rate and efficiency of gain and liver Cu stores of weanling pigs. The pigs were housed in groups of five to six/pen and fed a fortified, unmedicated, corn-soybean meal-dried whey basal diet (1.1% lysine, 30 ppm Cu). In Exp. 1 and 2, pigs (eight replicates) were fed the basal or the basal plus 125 or 250 ppm Cu from CuSO4 or CuO for 28 d. In Exp. 3 and 4, four replications were fed the same diets as in Exp. 1 and 2 plus two additional diets (500 ppm Cu from CuSO4 or CuO). In Exp. 5, dietary levels of 0, 125, 250, 375 or 500 ppm Cu from CuSO4 were evaluated using four replications. At the end of each experiment, the liver from one pig in each pen was collected for Cu analysis. Overall, rate and efficiency of gain were improved (P less than .01) by feeding 125 or 250 ppm Cu as CuSO4, with the 125 ppm dietary level being about 75% as effective in stimulating growth as 250 ppm. Performance of pigs was not different from controls when the highest (500 ppm) level of Cu (from CuSO4) was fed. Liver Cu increased 10- to 70-fold when 250 to 550 ppm Cu from CuSO4 was included in the feed.(ABSTRACT TRUNCATED AT 250 WORDS)

show abstract

Effects of High Levels of Copper and Chlortetracycline on Performance of Pigs

Cited by 30 publications

References 0 publications

Effects of Copper Sulfate and Ferrous Sulfide on Performance and Liver Copper and Iron Stores of Pigs

Effects of Copper Sulfate and Ferrous Sulfide on Performance and Liver Copper and Iron Stores of Pigs

Effect of High-Level Copper Feeding on the Sulfur Amino Acid Need of Chicks Fed Corn-Soybean Meal and Purified Crystalline Amino Acid Diets

Effects of Source and Level of Copper on Performance and Liver Copper Stores in Weanling Pigs

Contact Info

Product

Resources

About