Effects of High Risk Pregnancy Factors on Pelvic Floor Muscle Weakness and Changes of PG, ACTH and CRP

Abstract

Objective: To investigate the effects of different delivery modes on perinatal pelvic floor muscle strength, PG, ACTH and CRP of high-risk pregnant women. Methods: 380 high-risk pregnant women who gave birth in our hospital from March 2021 to February 2022 were selected as subjects, including 100 vaginal natural delivery, 156 forceps assisted delivery and 124 cesarean section. Pelvic floor pressure, PG, ACTH, CRP, IL-6, TNF-α and IL-4, IL-10 levels were evaluated and compared. The perinatal occurrence of pelvic floor functional disease (PFD) in high-risk pregnant women in each group was analyzed and evaluated. Results: There were statistical differences in the amount of postpartum blood loss (P < 0.0001, F = 99.01), postpartum blood loss 24 h (P = 0.0004, F = 19.54) and hospital stay (P < 0.0001, F = 70.81) among the three groups of high-risk women in natural vaginal delivery, forceps delivery and cesarean section. In addition, there were 72, 134 and 70 cases of abnormal pelvic floor fatigue in natural vaginal delivery, forceps assisted delivery and cesarean section (P < 0.0001, χ 2 = 30.16). There were 36, 79 and 21 cases of muscle injury, respectively (P < 0.0001, χ 2 = 34.16). There were 49, 98 and 43 cases of dysmuscular contraction, respectively (P < 0.0001, χ 2 = 21.94). There were 65, 120 and 41 cases with vaginal dynamic pressure < 80 cm H 2 O (P < 0.0001, χ 2 = 56.86), respectively. There were 78, 138 and 80 cases of Class I muscle fiber damage, respectively (P < 0.0001, χ 2 = 24.47). There were 67 cases, 132 cases and 66 cases of Class II muscle fiber damage, respectively (P < 0.0001, χ 2 = 30.42). Pairwise comparison among the three groups showed statistically significant differences. There were 15, 42 and 5 cases of SUI among the three groups, and there was a significant difference among the three groups (P < 0.0001, χ 2 = 29.90