2021
DOI: 10.1007/s00056-021-00318-x
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Effects of histamine and various histamine receptor antagonists on gene expression profiles of macrophages during compressive strain

Abstract: Purpose Tissue hormone histamine can accumulate locally within the periodontal ligament via nutrition or may be released during allergic reactions by mast cells, which may have an impact on orthodontic tooth movement. In addition to periodontal ligament fibroblasts, cells of the immune system such as macrophages are exposed to compressive strain. The aim of this study was thus to investigate the impact of histamine on the gene expression profile of macrophages in the context of simulated orthodon… Show more

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