Effects of HIV Status and Other Variables on the Outcome of Tuberculosis Treatment in Spain

Desfecho do tratamento e confirmação laboratorial do diagnóstico de tuberculose em pacientes com HIV/AIDS no Recife, Pernambuco, Brasil

“…(14)(15)(16) Regarding all outcomes observed, the percentage of cure in the present study was 58.7%, similar to that found in another study conducted in the city of Campinas, Brazil, (13) according to which the cure rate was 57.6% among TB/HIV co-infected patients. A lower percentage (43.4%) was found in another study (17) involving TB/HIV co-infected patients in Spain.…”

“…(13) In our study, the mortality rate was high (29%), which is intermediate between the 38.9% reported in the Malaysia study (12) and the 21.5% reported in the study conducted in Spain. (17) Since the Correia Picanço Hospital is a referral center, the condition of the patients treated at this hospital is critical, and the diagnosis, or suspected diagnosis, of TB/ HIV co-infection is usually made when the infection is in an advanced stage. This is confirmed by the findings of a study conducted in the northeast of Brazil, (20) in which half of the HIV/AIDS patients already presented signs or symptoms of immunosuppression when they arrived at specialized clinics, suggesting that the diagnosis and the treatment of HIV infection are both delayed.…”

Factores de riesgo asociados a los resultados potencialmente insatisfactorios y a la mortalidad durante el tratamiento antituberculoso en España

“…Los datos de nuestro estudio muestran que los principales factores de riesgo para el RPI en los casos españoles fueron el tratamiento previo y la coinfección con VIH, ya descritos en otros estudios 12,19,26 . También carecer de información sobre los resultados de cultivo o del estatus de tratamiento se asocia a peores resultados, lo que puede reflejar deficiencias en el seguimiento.…”

“…Mientras que unos incluían en el grupo de RPI los traslados y las pérdidas en el seguimiento, otros solo consideraron los fallos terapéuticos y abandonos, y algunos excluyeron del cálculo los casos sin información. Esta diversidad de criterios también se pone de manifiesto en los estudios realizados en España [10][11][12]26 .…”

Determinants of Treatment Failure Among Tuberculosis Patients on Directly Observed Theraphy in Rural Primary Health Care Centres in Ogun State, Nigeria

“…The period of about one year used to monitor HIV shows that HIV is not a major factor in TB treatment failure though this may not be conclusive. However, some studies have suggested that HIV is the strongest predictor of progression from latent TB infection to active disease [20][21][22][23][24]. The emergencies of more interaction of TB with human immunodeficiency virus (HIV) infection might be one of the reasons.…”