Effects of human chorionic gonadotropin and intravaginal progesterone device treatment after artificial inseminations on the reproductive performance of normal and repeat breeder lactating dairy cows

Abstract

We examined the effects of human chorionic gonadotropin (hCG) treatment on Day 5 (Day 0 = day of artificial insemination: AI) and intravaginal progesterone device (IVPD) treatment from Day 5 to 19 on the conception and detection rates of return to estrus (re-estrus) in lactating dairy cows. A total of 306 cows from a commercial dairy farm were divided into the following three groups on Day 5: non-treatment group (n = 128), untreated; hCG group (n = 71), 3,000 IU hCG was administered (intramuscularly); IVPD group (n = 107), IVPD was inserted into the vagina from Day 5 to 19. Re-estrus detection was performed up to Day 25. Pregnancy was diagnosed by rectal palpation between Day 50 and 60. There was an interaction between treatment and AI number (P < 0.01) on the conception rate of first-AI. For cows with more than three AIs, the IVPD treatment (66.7%) was more effective than the non-treatment (23.1%) (P < 0.05). The re-estrus detection rate was significantly (P < 0.05) higher in the IVPD group (60.7%) than that in the non-treatment group (41.4%) and tended (P < 0.1) to be higher than that in the hCG group (37.8%). Our results suggested that the conception rate can be improved by IVPD treatment, especially in cows with more than three AIs. In addition, IVPD treatment can induce higher estrus expression up to 25 days after AI in non-pregnant cows.

Therapy of Human Chorionic Gonadotropin (hCG) Hormone in Dairy Cattles that Have Repeat Breeder on Pregnancy Rate in Tulungagung, East Java, Indonesia

“…is not yet complete after giving birth is also one of the causes of embryo death during lactation, the uterine wall during the implantation process so that it is easy to die of the embryo 14 . In repeat breeder cases with failed implantation on day 28, the most cases occurred because of mild infections or subclinical endometritis which made the uterine temperature uncomfortable, therefore hCG hormone was given to keep the growth of the corpus luteum growing and accelerate the growth of the corpus luteum to produce progesterone, the hormone progesterone functions to maintain pregnancy and prevents contractions in the uterus and the fetus does not abort 15,16 . The administration of the hCG hormone at five days after IB aims to increase the level of hCG in the blood.…”

“…Low reproductive efficiency in dairy cows indicates reproductive problems, one of which is repeat breeder with cases of ovulation failure on day 21 and cases of implantation failure on day 28. Cows that experience repeat breeders are generally characterized by long calving intervals (18-24 months), low conception rates (<40%), and high service per conception (>3) 5,6,7 .…”