Effects of Human Genetic Factors (Ethnicity and Race) on Clinical Severity of SARS-CoV-2 (COVID-19)

Abstract

Coronavirus which is caused by SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) has been declared as a pandemic by the World Health Organization (WHO) on 11 March 2020. After the declaration, SARS-CoV-2 took its place in the scientific area. It is a striking fact about COVID-19 pandemic that mortality, morbidity, and severity of the infection differ from region to region and even from country to country. The reason for this case is that interaction between COVID-19 and human cell receptors, inflammation, complement, and coagulation responses in humans differs as a consequence of ethnicity and genetic diversity. In this review, the effects of gene variations dependent on ethnicity on the clinical course of SARS-CoV-2 is aimed to analyze.

Non-COVID-19 viral pneumonia in adults in Turkey

“…In Turkey, the National Sentinel Surveillance Network was established by the Republic of Turkey Ministry of Health, General Directorate of Public Health, Department of Infectious Diseases in 2005, and influenza surveillance has been carried out ever since. However, the latest information obtained was from 24 February -1 March 2020, and it was thought that updates could not be processed due to the coronavirus disease 2019 (COVID-19) pandemic [18] and increased workload. The latest data show that the dominant viruses in Turkey vary according to geographical regions during the flu season.…”