Effects of human mobility, temperature and mosquito control on the spatiotemporal transmission of dengue

Zhu, Guanghu; Liu, Tao; Xiao, Jianpeng; Zhang, Bing; Song, Tie; Zhang, Yonghui; Lin, Lifeng; Peng, Zhiqiang; Deng, Aiping; Hao, Yuantao

doi:10.1016/j.scitotenv.2018.09.182

Cited by 65 publications

(51 citation statements)

References 46 publications

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“…The logistic regression results show that in the municipality of Arauquita there is a higher risk of finding individuals infected with arboviruses ( Figure 4B). In accordance with our results, different models (Barmak et al, 2016;Massaro et al, 2019;Zhu et al, 2019) show that human mobility is an important factor for the increase in the incidence of DENV even over short distances, i.e., between cities. Considering the aforementioned, the municipality of Arauquita is in a border area with Venezuela, and therefore, there is a high movement of humans that may maintain the virus in these areas.…”

Section: Discussionsupporting

confidence: 91%

Identification of Aedes (Diptera: Culicidae) Species and Arboviruses Circulating in Arauca, Eastern Colombia

et al. 2020

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The identification of vector species and their natural infection with arboviruses results in important data for the control of their transmission. However, for the eastern region of Colombia, this information is limited. Therefore, this study morphologically and molecularly identified species of the genus Aedes and the detection of arboviruses (Dengue, Chikungunya, Zika, and Mayaro) in female mosquitoes (individually) present in three municipalities (Saravena, Arauquita, and Tame) by amplifying the genetic material using RT-PCR (reverse transcriptase polymerase chain reaction) in the department of Arauca, eastern Colombia. Inconsistencies between morphological and molecular identification were detected in 13 individuals with Aedes albopictus initially determined as Aedes aegypti based on morphology (n = 13). Molecular identification showed the simultaneous presence of A. aegypti (n = 111) and A. albopictus (n = 58) in the urban municipalities of Saravena and Arauquita. These individuals were naturally infected with Dengue virus type 1 (DENV-1) and Chikungunya virus (CHIKV). The most frequent arbovirus was DENV-1 with an infection rate of 40.7% (11/27) for A. aegypti and 39.7% (23/58) for A. albopictus, which was followed by CHIKV with an infection rate of 1.8% for A. aegypti (2/111) and 6.9% for A. albopictus (4/58). Additionally, a mixed infection of DENV-1 and CHIKV was obtained in 4.5% of A. aegypti (5/111). Zika virus (ZIKV) and Mayaro virus (MAYV) infections were not detected. This study found that barcoding (fragment gene COI) is a successful method for identifying Aedes species. Additionally, we recommend the individual processing of insects as a more accurate strategy for arboviruses detection since the infection rate is obtained and co-infection between DENV-1 and CHIKV is also possible.

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Section: Discussionsupporting

confidence: 91%

Identification of Aedes (Diptera: Culicidae) Species and Arboviruses Circulating in Arauca, Eastern Colombia

et al. 2020

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“…The temperature has a prominent role in viral replication, adult vector survival, and infective periods [62,63]. Increased survival and/or migration of vectors into previously non-endemic geographic areas outside the tropics have resulted from increased temperature.…”

Section: Climate Change Factorsmentioning

confidence: 99%

The Dengue Vaccines: Assessment of Future Prospects, Treatment, and Vaccine Challenges

KALYANI

Thanushree

2020

Asian J Pharm Clin Res

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Objectives: As per the national survey data, the prevalence of dengue has been still rising consistently, and the burden of the disease is predominantly affecting the adults with progression toward the DF, dengue hemorrhagic fever, and dengue shock syndrome. The higher hospitalization rate result in massive mortality. Methods: Vector control alone cannot reduce the transmission of viral infection, so effective vaccine development is made high priority. Results: Several vaccine candidates including live attenuated, live chimeric, inactivated and many other vector vaccines are key elements needed to achieve the dengue public health targets. Global strategies like diagnosis, care management, outbreak preparedness and integrated surveillance, sustainable vector control, and future vaccine implementation are needed to be addressed. Conclusion: This review mainly describes the dengue treatment challenges, in addition to a brief discussion of dengue vaccine challenges and future outlook on dengue that might help in making efficacious vaccine in near future.

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“…Even as effective vaccines become available, vector control is crucial in dengue prevention and mitigation [ 10 , 11 ]. Previous studies have reported the effectiveness of interventions which included vector control measures in locations such as two Chinese cities of Guangzhou [ 12 , 13 ] and Ningbo [ 14 ], Sri Lanka [ 15 ], and Singapore [ 16 ]. In addition, Liu et al illustrated that the implementation of early rigorous interventions could reduce dengue epidemic through simulating dengue incidences under different scenarios [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

The effectiveness of early start of Grade III response to dengue in Guangzhou, China: A population-based interrupted time-series study

Liu

Zhang

et al. 2020

PLoS Negl Trop Dis

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In 2019, dengue incidences increased dramatically in many countries. However, the prospective growth in dengue incidence did not occur in Guangzhou, China. We examined the effectiveness of early start of Grade III response to dengue in Guangzhou. We extracted the data on daily number of dengue cases during 2017–2019 in Guangzhou and weekly data for Foshan and Zhongshan from the China National Notifiable Disease Reporting System, while the data on weekly number of positive ovitraps for adult and larval Aedes albopictus were obtained from Guangzhou Center for Disease Control and Prevention. We estimated the number of dengue cases prevented by bringing forward the starting time of Grade III response from September in 2017–2018 to August in 2019 in Guangzhou using a quasi-Poisson regression model and applied the Baron and Kenny’s approach to explore whether mosquito vector density was a mediator of the protective benefit. In Guangzhou, early start of Grade III response was associated with a decline in dengue incidence (relative risk [ RR ]: 0.54, 95% confidence interval [CI]: 0.43–0.70), with 987 (95% CI: 521–1,593) cases averted in 2019. The rate of positive ovitraps also significantly declined ( RR : 0.64, 95% CI: 0.53–0.77). Moreover, both mosquito vector density and early start of Grade III response was significantly associated with dengue incidence after adjustment for each other. By comparing with the incidence in Foshan and Zhongshan where the Grade III response has not been taken, benefits from the response starting in August were confirmed but not if starting from September. Early start of Grade III response has effectively mitigated the dengue burden in Guangzhou, China, which might be partially through reducing the mosquito vector density. Our findings have important public health implications for development and implementation of dengue control interventions for Guangzhou and other locations with dengue epidemics.

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Effects of human mobility, temperature and mosquito control on the spatiotemporal transmission of dengue

Cited by 65 publications

References 46 publications

Identification of Aedes (Diptera: Culicidae) Species and Arboviruses Circulating in Arauca, Eastern Colombia

Identification of Aedes (Diptera: Culicidae) Species and Arboviruses Circulating in Arauca, Eastern Colombia

The Dengue Vaccines: Assessment of Future Prospects, Treatment, and Vaccine Challenges

The effectiveness of early start of Grade III response to dengue in Guangzhou, China: A population-based interrupted time-series study

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