In the first of two experiments, periods of noise were terminated with unavoidable shock to 36 rats. The rats' continuously reinforced responding was later completely suppressed during the noise when it was introduced without shock. The rats were then assigned to nine experimental groups. Each group was exposed to different paced variable-interval schedules of reinforcement, which independently controlled response rate and reinforcement frequency. Periods of the noise were periodically superimposed on these schedules, and loss of response suppression was studied. Differences between the groups were assessed statistically. The second experiment used a steady-state design. Six rats were exposed to paced schedules which generated two alternating response rates but gave constant reinforcement frequencies, and six rats to schedules which maintained the same response rates throughout, but in which the reinforcement frequency was alternately high and low. Response suppression was studied during a pre-shock stimulus superimposed on each rat's two behavioral baselines. Both experiments suggest that (1) conditioned suppression is affected by rate of operant responding, high rates being most suppressed, and (2) the frequency of reinforcements obtained also has an effect, most suppression occurring when frequency is low.