The true strain data and true stress data are obtained from the isothermal compression tests under a wide range of strain rates (0.1–20 s−1) and temperatures (933–1,133 K) over the Gleeble-3500 thermomechanical simulator. The data are employed to generate the constitutive equations according to four constitutive models, respectively, the strain-compensated Arrhenius-type model, the modified Zerilli–Armstrong (ZA) model, the modified Johnson–Cook (JC) model and the JC model. In the meanwhile, a comparative research was made over the capacities of these four models and hence to represent the elevated temperature flow behavior of TA2. Besides, a comparison of the accuracy of the predictions of average absolute relative error, correlation coefficient (R) and the deformation behavior was made to test the sustainability level of these four models. It is shown from these results that the JC model is not suitable for the description of flow behavior of TA2 alloy in α+β phase domain, while the predicted values of modified JC model, modified ZA model and the strain-compensated Arrhenius-type model could be consistent well with the experimental values except under some deformation conditions. Moreover, the strain-compensated Arrhenius-type model can be also used to track the deformation behavior more precisely in comparison with other models.