Effects of individualised homoeopathic intervention in Stage I essential hypertension: A single-blind, randomised, placebo-controlled trial

Varanasi, Roja; Kolli, Raju; Rai, Yogendra; Ramesh, D; Kiranmayee, Rompicherla Gr; Reddy, G Ravi Chandra; Baig, H; Patole, Tejaswini; Srivastava, Priyanka; Bhalaerao, Rupali; Chaudhary, Anupriya; Kumar, Arvind; Sarathy, V; Jayasri, GR; Sachdeva, Garima; Jain, Saurabh Kumar; Sharma, Neha; Amsole, Sucharitha; Oinam, Amita; Oberai, Praveen; Manchanda, Raj K

doi:10.4103/ijrh.ijrh_93_19

Cited by 6 publications

(4 citation statements)

References 12 publications

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“…23 A randomized, single-blind, placebo-controlled trial found the LM potencies to be effective in controlling stage I HTN. 24 Natrum muriaticum came as one of the most frequently indicated medicines in all four trials. In comparison with all the trials of homeopathy in HTN, ours was focused on immediate control of BP instead of long-term control.…”

Section: Discussionmentioning

confidence: 99%

“…18 There is an increasing trend for personalized treatment 19 and complementary and alternative medicine (CAM) therapies including homeopathy for various chronic diseases including HTN, 20 but no systematic review or meta-analysis supporting the use of homeopathy in HTN could be identified. All of the conducted trials of homeopathy in HTN have focused on long-term sustainable management, [21][22][23][24] but not in immediate management.…”

Section: Introductionmentioning

confidence: 99%

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A Randomized Trial of Three Homeopathic Drugs: Rauwolfia serpentina, Viscum album, and Spartium scoparium in Essential Hypertension

Mandal,

Maity,

Shaikh

et al. 2023

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Hypertension (HTN) remains one of the major risk factors for heart failure, stroke, and coronary heart disease worldwide. This study was undertaken to compare the antihypertensive effects produced by the mother tinctures (MTs) of three homeopathic drugs—Rauwolfia serpentina (RS), Viscum album (VA), and Spartium scoparium (SS; also known as Cytisus scoparius [CS]) in essential hypertension. This open-label, randomized, three parallel arm, pragmatic, pilot trial was conducted on 60 participants with essential hypertension in the outpatient department of D. N. De Homoeopathic Medical College and Hospital, Kolkata. Participants were randomized into three groups: RS, VA, and SS equally. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured at baseline and after 30 and 60 minutes. Group differences at different time points and overall were measured using one-way analysis of variance (ANOVA) and three-way repeated measure ANOVA models, respectively, after adjusting for baseline differences using intention-to-treat approaches. A p value less than 0.05 was considered statistically significant. Endpoint analysis included 60 participants. Although the highest mean reductions in SBP and DBP with time were achieved in the RS group, all three medicines revealed similar antihypertensive effects without any significant differences (SBP: F 2, 57 = 1.710, p = 0.190; DBP: F 2, 57 = 0.732, p = 0.485). No harm or serious adverse events were reported from either of the groups. All three medicines (RS, VA, and SS) produced similar antihypertensive effects in essential hypertension. Trial registration: CTRI/2021/02/031548; UTN: U1111–1264–6856.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A Randomized Trial of Three Homeopathic Drugs: Rauwolfia serpentina, Viscum album, and Spartium scoparium in Essential Hypertension

Mandal,

Maity,

Shaikh

et al. 2023

Homœopathic Links

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show abstract

“…Family history is a positive risk factors among hypertensive patients [38,39] . Medica also suggest that these medicines have potent effect on reducing blood pressure [40,41] . From this study it was also subjected that Terminalia arjuna can also be given in management of primary hypertension.…”

Section: Family Historymentioning

confidence: 99%

A randomized comparative interventional study to assess the efficacy of individualized homoeopathic medicine and Terminalia arjuna in cases of primary hypertension

Dabi

2024

Int. J. Homoeopathic Sci.

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Background: Hypertension is considered to be silent killer as it is largely asymptomatic and patient may have elevated blood pressure for a long time. Hypertension is a grave medical condition, elevating the risks of heart, brain, kidney, and other diseases. Approximately 1.28 billion adults aged 30-79 worldwide grapple with hypertension, with the majority (two-thirds) residing in low-and middleincome countries. Alarmingly, an estimated 46% of adults with hypertension are unaware of their condition. Diagnosis and treatment rates remain low, with less than half (42%) of adults with hypertension being identified and treated. Objective• To assess the extent of improvement in cases of primary hypertension receiving individualized homoeopathic medicines.• To assess the extent of improvement in cases of primary hypertension receiving predefined Homoeopathic medicine Terminalia arjuna.• To compare between extent of improvement in both the cases.Study Design: Comparative interventional study. Methods: In each group, 45 cases of Primary hypertension were selected on the basis of inclusion and exclusion criteria. Patients in Group A were prescribed individualized homoeopathic medicine while those in Group B received predefined homoeopathic medicine Terminalia arjuna. Assessment and reassessments were done by measuring difference in mean arterial pressure before and after treatment. Results: Primary hypertension was found to be more common in age group between 50 -60 years, middle socio-economic and rural population. After treatment in Group A, the overall improvement percentage was 84% in which 26% showed marked improvement; 33.33% showed moderate improvement; and 24.44% showed mild improvement observed through decrease in mean arterial pressure. In group B, the improvement percentage was 68%, in which 22% showed marked improvement, 15% showed moderate improvement and 31% showed mild showed improvement observed through decrease in mean arterial pressure. A Paired samples t-test was conducted in both groups to compare pre and post mean arterial pressure. In Group A significant difference in mean arterial pressure was observed post treatment (M=105.71, SD=4.284), compared to pre-treatment (M=123.79, SD=6.434). Group B receiving predefined medicine Terminalia arjuna, decrease in mean arterial pressure post treatment (M=107.07, SD=3.984), compared to pre-treatment (M=121.38, SD=6.629), also showed significant difference. Thus, statistical result showed that there was significant difference in pre and post mean arterial pressure in both groups. This suggests that homoeopathic medicines were very effective in the treatment of Primary hypertension. An independent t-test war carried out to compare post treatment decrease in mean arterial pressure in both groups showed that extent of improvement was better in constitutional medicines group than second group in which Terminalia arjuna was given. Conclusion:In this study, it was found that there is statistically significant difference in mean arterial pressure before and after treatm...

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“…The authors suggest that the psychological connection in patients with essential hypertension along with standard outcome assessment should be done to find cause oriented relationship and management by homoeopathy in such cases should be explored. [8] A paper by Dr. Sultana Perween and Dr. Shamim Alam in 2020 deals with role of Homoeopathy in Hypertension. They have expressed their opinions of how homoeopathic management of hypertension could be done.…”

Section: Introductionmentioning

confidence: 99%

Homoeopathic management of stress of essential hypertension patients : A literature review

Patil

Nerlekar

2023

Sust. Agric. Food Env. Res.

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Hypertension kills insidiously as it is commonly asymptomatic. Stress is conceived to be a significant contributing element towards development of essential hypertension. Homeopathy being the second largest system of medicine has immense scope, allowing in depth study of stress and offering individualized approach to these cases of stress led essential hypertension. There are several homoeopathic medicines which could prove useful in managing stress of essentialhypertension. This article attempts to review some of the existing literature in this context discussing role of homoeopathy in management of stress of essential hypertension patients.

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Effects of individualised homoeopathic intervention in Stage I essential hypertension: A single-blind, randomised, placebo-controlled trial

Cited by 6 publications

References 12 publications

A Randomized Trial of Three Homeopathic Drugs: Rauwolfia serpentina, Viscum album, and Spartium scoparium in Essential Hypertension

A Randomized Trial of Three Homeopathic Drugs: Rauwolfia serpentina, Viscum album, and Spartium scoparium in Essential Hypertension

A randomized comparative interventional study to assess the efficacy of individualized homoeopathic medicine and Terminalia arjuna in cases of primary hypertension

Homoeopathic management of stress of essential hypertension patients : A literature review

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