Effects of indoor painting and smoking on airway symptoms in atopy risk children in the first year of life results of the LARS-study

Diez, Ulrike; Kroessner, T.; Rehwagen, M.; Richter, Matthias; Wetzig, H.; Schulz, R.; Borte, Michael; Metzner, G; Krumbiegel, P.; Herbarth, Olf

doi:10.1078/s1438-4639(04)70004-8

Cited by 134 publications

(114 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Diez et al (151) studied 266 newborn children born with birth weight of 1,500-2,500 g, or with elevated IgE in cord blood, or with a positive primary family history of atopic disease. Concentrations of 25 VOCs were monitored indoors during the first 4 weeks of life.…”

Section: Epidemiologic Evidence For Voc Mixturesmentioning

confidence: 99%

Epidemiologic evidence for asthma and exposure to air toxics: linkages between occupational, indoor, and community air pollution research.

Delfino

2002

Environ Health Perspect

269

152

View full text Add to dashboard Cite

Outdoor ambient air pollutant exposures in communities are relevant to the acute exacerbation and possibly the onset of asthma. However, the complexity of pollutant mixtures and etiologic heterogeneity of asthma has made it difficult to identify causal components in those mixtures. Occupational exposures associated with asthma may yield clues to causal components in ambient air pollution because such exposures are often identifiable as single-chemical agents (e.g., metal compounds). However, translating occupational to community exposure-response relationships is limited. Of the air toxics found to cause occupational asthma, only formaldehyde has been frequently investigated in epidemiologic studies of allergic respiratory responses to indoor air, where general consistency can be shown despite lower ambient exposures. The specific volatile organic compounds (VOCs) identified in association with occupational asthma are generally not the same as those in studies showing respiratory effects of VOC mixtures on nonoccupational adult and pediatric asthma. In addition, experimental evidence indicates that airborne polycyclic aromatic hydrocarbon (PAH) exposures linked to diesel exhaust particles (DEPs) have proinflammatory effects on airways, but there is insufficient supporting evidence from the occupational literature of effects of DEPs on asthma or lung function. In contrast, nonoccupational epidemiologic studies have frequently shown associations between allergic responses or asthma with exposures to ambient air pollutant mixtures with PAH components, including black smoke, high home or school traffic density (particularly truck traffic), and environmental tobacco smoke. Other particle-phase and gaseous co-pollutants are likely causal in these associations as well. Epidemiologic research on the relationship of both asthma onset and exacerbation to air pollution is needed to disentangle effects of air toxics from monitored criteria air pollutants such as particle mass. Community studies should focus on air toxics expected to have adverse respiratory effects based on biological mechanisms, particularly irritant and immunological pathways to asthma onset and exacerbation.

show abstract

Section: Epidemiologic Evidence For Voc Mixturesmentioning

confidence: 99%

Epidemiologic evidence for asthma and exposure to air toxics: linkages between occupational, indoor, and community air pollution research.

Delfino

2002

Environ Health Perspect

269

152

View full text Add to dashboard Cite

show abstract

“…Foetal growth, male gender, neonatal lung function, maternal age, breastfeeding, family history of asthma or atopy, day care attendance, number of siblings, tobacco smoke exposure, air pollution, socio-economic status and pet keeping are associated with wheezing illnesses [13][14][15][16][17][18][19][20]. Unfortunately, easily applicable scores to reliably estimate the risk to develop wheezing illnesses in healthy newborns are not available [21].…”

Section: Rationalementioning

confidence: 99%

The Wheezing Illnesses Study Leidsche Rijn (WHISTLER): Rationale and Design

et al. 2003

View full text Add to dashboard Cite

Abstract. The Wheezing Illnesses Study Leidsche Rijn (WHISTLER) was initiated in December 2001 as a single-centre prospective birth cohort study and will include a population-based sample of at least 2000 healthy newborns. The aims of WHISTLER are to investigate determinants for wheezing illnesses (including neonatal lung function, viral infections, asthma-susceptibility genes and endotoxin exposure) and to derive a comprehensive risk score, that is appropriate for use in primary health care and allows for efficient planning of early preventive strategies. Baseline examination includes a questionnaire evaluating known risk factors for wheezing illnesses; anthropometric measurements; measurements of infant and parental lung function; and sampling of infant and parental DNA. Participants will be followed for respiratory events using data from a daily respiratory symptom questionnaire; visits to the general practitioner (primary health care visits, drugs prescriptions and hospital referral); viral sampling during wheezing episodes; and house dust sampling. Based on actual neonatal care practice and embedded in a larger epidemiological study, the Utrecht Health Project, WHISTLER will provide an unique framework to address issues in childhood respiratory disease that are currently insufficiently understood. In particular, WHISTLER will provide a well-balanced view on the prognostic power of neonatal lung function and genetic and environmental factors (including viral infections and endotoxin exposure) to predict wheezing illnesses from birth to young adulthood and beyond. In the scope of prevention, WHISTLER is expected to support the design of solid based prevention measures to reduce respiratory morbidity, mortality and associated costs, and to improve quality of life.

show abstract

“…(Zhang et al, 2011). (Diez et al, 2000). 그러나 사무실 작업자들을 대상으로 한 연구 에서는 VOC의 농도와 알레르기 비염은 관련성이 없 는 것으로 나타났다 (Rios et al, 2010).…”

unclassified

Indoor Air Quality in Elementary School Children's Homes in Ulsan: Comparison between Groups with and without Allergic Rhinitis

Lee¹,

Lee²,

Oh³

et al. 2012

Journal of Korean Society for Atmospheric Environment

View full text Add to dashboard Cite

This study compared indoor air quality of homes in which elementary school children with and without (case and control) allergic rhinitis live in the Ulsan metropolitan region (UMR). A total of 58 homes (case and control: 29, respectively; children aged 7 to 12 years) was selected for indoor air quality measurements. The concentrations of all general indoor air pollutants, except PM 2.5 , in the case group were much higher than those in the control group. In particular, the average concentrations of O 3 and NO 2 in the case group were statistically significantly (p⁄0.05) higher than those in the control group. Average concentrations of CO 2 in the case and control groups and NO 2 in the case group exceeded the standard level. Some components of aldehydes and ketones and VOCs indicated large difference of average concentrations between two groups, but there were no statistically significant differences.

show abstract

Effects of indoor painting and smoking on airway symptoms in atopy risk children in the first year of life results of the LARS-study

Cited by 134 publications

References 10 publications

Epidemiologic evidence for asthma and exposure to air toxics: linkages between occupational, indoor, and community air pollution research.

Epidemiologic evidence for asthma and exposure to air toxics: linkages between occupational, indoor, and community air pollution research.

The Wheezing Illnesses Study Leidsche Rijn (WHISTLER): Rationale and Design

Indoor Air Quality in Elementary School Children's Homes in Ulsan: Comparison between Groups with and without Allergic Rhinitis

Contact Info

Product

Resources

About