Effects of Infrared Combined with Methylcobalamin on the Vibratory Sensory Threshold and Nerve Conduction Velocity of the Lower Extremity in Patients with Diabetic Foot Treatment

Abstract

Objective. To investigate the effect of infrared combined with methylcobalamin on the vibratory sensory threshold and lower limb nerve conduction velocity of patients with diabetic foot. Methods. One hundred and six patients with diabetic foot in our hospital from February 2018 to December 2020 were enrolled and divided into the study and control groups. The patients in the control group were given methylcobalamin, and the patients in the research group were treated with infrared light on the basis of the control group. The therapeutic effect, vibration sensory threshold, lower limb nerve conduction velocity, and related biochemical index levels before and after treatment in the two groups were counted. Result. The total effective rate of the study group (94.34%) was significantly higher than that of the control group (81.13%). The left/right lower limb vibration sensation threshold decreased in both groups after treatment, and the study group was lower than that of the control group ( P < 0.05 ). The conduction velocity of the left/right common peroneal nerve and tibial nerve increased in both groups after treatment, and the study group was larger than that of the control group ( P < 0.05 ). The bFGF, VEGF, and APN increased in both groups after treatment. VEGF and APN increased and IL-6 and TNF-α decreased in both groups after treatment, and the study group was better than the control group ( P < 0.05 ). Conclusion. Infrared and methylcobalamin combined treatment of diabetic foot can effectively improve lower extremity nerve conduction velocity and vibration sensory threshold, regulate serum bFGF and VEGF levels, reduce the degree of inflammatory response, and help improve the overall treatment effect.

Advances in microcirculation monitoring and physical factor therapy techniques in diabetic foot

“…Yi Wang et al [26] used the KP-220 infrared therapy instrument (Power 32mW/cm², Wavelength 2-25um) combined with methylcobalamin irradiation for diabetic foot patients. The control group received daily methylcobalamin injections, while the study group underwent infrared therapy in addition to the standard treatment for 4 weeks.…”

Efficacy of Sitagliptin and Recombinant Bovine Basic Fibroblast Growth Factor Gel in the Treatment of Chronic Diabetic Foot Ulcers

“…Recombinant bovine basic Fibroblast Growth Factor (rb-bFGF) gel can repair wounds, promote tissue regeneration and improve local microcirculation, thus accelerating wound healing [7] . Previous studies believed that during the pathological process, the lower extremity blood vessels of DFU patients would be in chronic inflammatory state and there would be secretion of inflammatory factors [8] . High-sensitivity C-Reactive Protein (hs-CRP) is an acute reactive protein that is strongly associated with the collective inflammatory response [9] .…”

Retracted: Effects of Infrared Combined with Methylcobalamin on the Vibratory Sensory Threshold and Nerve Conduction Velocity of the Lower Extremity in Patients with Diabetic Foot Treatment

“…This article has been retracted by Hindawi following an investigation undertaken by the publisher [ 1 ]. This investigation has uncovered evidence of one or more of the following indicators of systematic manipulation of the publication process: Discrepancies in scope Discrepancies in the description of the research reported Discrepancies between the availability of data and the research described Inappropriate citations Incoherent, meaningless and/or irrelevant content included in the article Peer-review manipulation …”

“…This article has been retracted by Hindawi following an investigation undertaken by the publisher [1]. This investigation has uncovered evidence of one or more of the following indicators of systematic manipulation of the publication process:…”