Effects of inhaled bronchodilators on lung function and cycling performance in female athletes with and without exercise-induced bronchoconstriction

Koch, Sarah; Karacabeyli, Derin; Galts, Ciaran; MacInnis, Martin J.; Sporer, Benjamin C.; Koehle, Michael S.

doi:10.1016/j.jsams.2014.07.021

Cited by 19 publications

(22 citation statements)

References 24 publications

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“…Although previous studies that have suggested this may be the case for salbutamol, the hypothesis has not been rigorously investigated. 31 Due to the relatively small number of females in our study, our data was underpowered to conduct meaningful sub analyses.…”

Section: Discussionmentioning

confidence: 98%

Improved Sprint Performance With Inhaled Long-Acting β2-Agonists Combined With Resistance Exercise

Merlini¹,

Whyte²,

Marcora³

et al. 2019

International Journal of Sports Physiology and Performance

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Purpose: To investigate the impact of twice-daily inhalation of 100 µg of salmeterol (SAL) or 12 µg of formoterol (FOR) in addition to a strength- and power-training program over a 5-wk period on a 30-m sprint, strength, power, mood, stress, and skinfold thickness. Methods: In a randomized, single-blind study, 23 male and 15 female nonasthmatic, recreationally active individuals were recruited (mean [SD] age 26.3 [5.4] y, weight 76.2 [11.5] kg, height 176.9 [8.5] cm). Participants completed 3 standardized whole-body strength- and power-training sessions per week for 5 wk during which they were assigned to an SAL, FOR, or placebo group. Participants used their inhaler twice per day as instructed and completed assessments of sprint, strength, and power at baseline and 1 wk after cessation of the training program. The assessments included a 30-m sprint, vertical jump, 1-repetition-maximum (1RM) bench press, 1RM leg press, peak torque flexion and extension, anthropometric evaluation, and Rest-Q questionnaires. Results: After 5 wk of strength and power training, 30-m sprint time reduced in the FOR (0.29 [0.11] s, P = .049) and SAL (0.35 [0.05] s, P = .040) groups compared with placebo (+0.01 [0.11] s). No significant change was found in other assessments of strength, mood, or skinfold thickness. Conclusions: When strength and power training are combined with the inhalation of FOR or SAL over a 5-wk period, moderately trained individuals experience an improvement in 30-m sprint performance.

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Section: Discussionmentioning

confidence: 98%

Improved Sprint Performance With Inhaled Long-Acting β2-Agonists Combined With Resistance Exercise

Merlini¹,

Whyte²,

Marcora³

et al. 2019

International Journal of Sports Physiology and Performance

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“…Finally, inadequate diagnosis and potential incongruence of asthma treatment with asthma diagnosis in athletes might be an issue since the World Anti-Doping Committee (WADA) and the International Olympic Committee removed the need to document asthma by lung function tests before the use of inhaled b2-agonists in 2009 [4]. However, the larger body of evidence suggests that b2-agonists within the controlled concentrations have no ergogenic effects and do not improve exercise performance [4,31,32].…”

Section: Discussionmentioning

confidence: 99%

Asthma prevalence in Olympic summer athletes and the general population: An analysis of three European countries

Burns

Mason

Mueller

et al. 2015

Respiratory Medicine

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“…Short-acting beta 2 agonists (SABA) are effective in preventing EIB when used 5 to 20 minutes before exercise (23,46,64). The effects lasts up to 2 h, but in 15-20 percent of patients with EIB, SABA may fail to prevent bronchoconstriction.…”

Section: Short-acting Beta 2 Agonistsmentioning

confidence: 99%

Exercise intolerance and exercise-induced bronchoconstriction in children

Minić

Sovtić

2017

Front Biosci

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Respiratory symptoms at rest or during exercise may restrain the physical capabilities required for normal motor and psychosocial development in children. The most frequent cause of exercise intolerance, apart from poor physical fitness, is exercise-induced bronchoconstriction (EIB), which may occur in some healthy children and in children with asthma. It is proposed that hyperventilation during exercise is associated with drying and cooling of airways, which can trigger a proinflammatory response. Several tests are used to confirm EIB, and the exercise-challenge test is the most common. Some nonpharmacologic therapies may induce airway refractoriness; warm-up exercise can result in the attenuation of EIB in more than half of the people with EIB. Prophylactic intermittent treatment with short-acting bronchodilators is the most commonly used treatment, but the conventional pharmacologic therapy for patients with uncontrolled asthma is the regular use of inhaled corticosteroids, with or without long-acting beta-agonists and montelukast. Therapy should result in optimal control of exercise-induced symptoms during habitual physical activity and also allow participation in sports activity in athletes.

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Effects of inhaled bronchodilators on lung function and cycling performance in female athletes with and without exercise-induced bronchoconstriction

Cited by 19 publications

References 24 publications

Improved Sprint Performance With Inhaled Long-Acting β2-Agonists Combined With Resistance Exercise

Improved Sprint Performance With Inhaled Long-Acting β2-Agonists Combined With Resistance Exercise

Asthma prevalence in Olympic summer athletes and the general population: An analysis of three European countries

Exercise intolerance and exercise-induced bronchoconstriction in children

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