Effects of initiating physician-performed germline testing in safety net clinic patients with epithelial ovarian cancer

Jordan, Scott; Spring, Samantha; Kamath, Priyanka; Schlumbrecht, Matthew; Pearson, J. Matt; Sinno, Abdulrahman K.; George, Sophia; Huang, Marilyn

doi:10.1016/j.gore.2020.100662

Cited by 2 publications

(1 citation statement)

References 17 publications

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“…Another study found that physician-performed genetic testing for ovarian cancer within a gynecologic oncology clinic was effective and shortened time to testing and result receipt. 21 Prior studies have indicated a discrepancy between the number of patients with prostate cancer who should undergo genetic testing and the number of patients who do undergo testing, indicating that removal of barriers to genetic testing is imperative. 20,22 This can in part be achieved by improved education of providers and development of systematic approaches to identifying eligible patients, ensuring inclusion of all patients who meet guidelines-based testing criteria.…”

Section: Discussionmentioning

confidence: 99%

Satisfaction With Clinician-Led Germline Genetic Counseling in Patients With Prostate Cancer

et al. 2022

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Purpose:Indications for germline testing in prostate cancer patients have expanded substantially over the past decade. With a near-universal shortage of genetic counselors and increasing demand, increased access to genetic counseling is crucial. We sought to prospectively implement and assess a clinician-led approach to genetic counseling and testing.Materials and Methods:Patients with metastatic or localized prostate cancer meeting National Comprehensive Cancer Network® criteria for consideration of genetic testing were offered pre-test genetic counseling by their urologist or medical oncologist as part of their routine clinical care and concurrently approached for enrollment in the Germline Genetics in Prostate Cancer Study. Consented patients filled out a post-counseling survey using validated instruments to assess the quality of counseling. For patients who elected to undergo genetic testing, an additional validated questionnaire was completed following disclosure of results. The primary outcome was the proportion of patients undergoing testing, with a target >60% of patients. The secondary outcome was overall satisfaction with counseling, with a target >85% of patients.Results:A total of 275 patients enrolled, and 203 patients elected to undergo genetic testing. Post-counseling surveys were obtained from 265 patients, and post-genetic testing surveys were obtained from 132 patients. Patient satisfaction was high, with 98% of patients reporting being satisfied with the overall quality of pre-test counseling, and 74% of patients elected to undergo genetic testing.Conclusions:These results support the effectiveness of clinician-led genetic counseling in prostate cancer. With clinician training, this approach can be utilized to expand access to appropriate germline genetic testing.

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Section: Discussionmentioning

confidence: 99%

Satisfaction With Clinician-Led Germline Genetic Counseling in Patients With Prostate Cancer

et al. 2022

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Genetic Predisposition for Gynecologic Cancers

González Peña,

Huang

2024

Clinical Obstetrics &Amp; Gynecology

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Hereditary cancer syndromes (HCS) are responsible for up to 10% of all cancers. At present, the majority of cancer susceptibility testing is initiated after a cancer diagnosis. There exists a significant opportunity for primary care providers including general obstetrician-gynecologists to engage in hereditary cancer risk assessment through adequate family history evaluation, initiation of genetic testing, and following the recommendations of national organizations. Identifying hereditary cancer genes may prompt primary prevention efforts such as enhanced screening, prevention, or personalized care strategies. We will review the literature regarding the approach and assessment of the most common gynecologic HCS.

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Effects of initiating physician-performed germline testing in safety net clinic patients with epithelial ovarian cancer

Cited by 2 publications

References 17 publications

Satisfaction With Clinician-Led Germline Genetic Counseling in Patients With Prostate Cancer

Satisfaction With Clinician-Led Germline Genetic Counseling in Patients With Prostate Cancer

Genetic Predisposition for Gynecologic Cancers

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