2023
DOI: 10.1155/2023/2523245
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Effects of Intensive Glycemic Control on Serum Exosome miR‐126‐3p and miR‐125b‐1‐3p Levels and Wound Healing in Patients with Diabetic Ulcers

Abstract: Objective. Intensive glycemic control and exosomal miRNAs have both been reported to improve wound repair in diabetic ulcers. In this study, we aimed to investigate the effects of intensive glycemic control on serum exosome microRNA-126-3p (miR-126-3p), microRNA-125b-1-3p (miR-125b-1-3p), and wound healing in patients with diabetic ulcers. Methods. Herein, 45 diabetic patients with an ulcer, aged 35–75 years old, were randomly assigned to the intensive glycemic control group (n = 21) and the conventional glyce… Show more

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