Effects of intradialytic cycling exercise on daily physical activity, physical fitness, body composition, and clinical parameters in high-volume online hemodiafiltration patients: a pilot randomized-controlled trial

Assawasaksakul, Nawaporn; Sirichana, Worawan; Joosri, Waraporn; Kulaputana, Onanong; Eksakulkla, Sukanya; Ketanun, Chutima; Kittiskulnam, Piyawan; Chantadisai, Maythinee; Takkavatakarn, Kullaya; Susantitaphong, Paweena; Praditpornsilpa, Kearkiat; Eiam‐Ong, Somchai; Tiranathanagul, Khajohn

doi:10.1007/s11255-020-02677-7

Cited by 20 publications

(33 citation statements)

References 38 publications

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“…All studies were randomized trials included in this meta-analysis. Among these studies, 12 trials ( 17 , 19 , 21 – 26 , 28 , 31 , 32 , 34 ) reported the concrete randomization methods. The performance bias was considered as high risk in all trials because it was impossible to blind the participants and researches for the exercise training.…”

Section: Resultsmentioning

confidence: 99%

“…Peak VO2 was compared in 10 trials ( 17 , 19 , 21 – 24 , 28 , 31 , 32 , 34 ). It significantly increased in the exercise training group compared with the usual control group (WMD, 2.64; 95% CI, 1.94–3.35, P < 0.00001; without heterogeneity: P = 0.24, I 2 = 22%, Figure 5 ).…”

Section: Resultsmentioning

confidence: 99%

“…CRP was compared in seven trials ( 17 , 21 , 23 , 25 , 29 – 31 ). The exercise training had no effect on the levels of CRP (WMD, −0.09; 95% CI, −0.26 to 0.09, P = 0.33; without heterogeneity: P = 0.57, I 2 = 0%, Supplementary Figure 3 ).…”

Section: Resultsmentioning

confidence: 99%

“…Among the studies, nine trials ( 17 , 19 , 22 , 24 – 28 , 31 , 34 ) reported no adverse events with exercise. Two trials ( 31 , 32 ) reported no difference in adverse events between exercise training groups and control group.…”

Section: Resultsmentioning

confidence: 99%

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Association of Exercise With Vascular Function in Patients With CKD: A Meta-Analysis of Randomized Controlled Trials

Wang

Xie

et al. 2022

Front. Med.

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Background and AimVascular function is associated with an increased risk of cardiovascular events in patients with chronic kidney disease (CKD). Whether exercise improves vascular function in such patients remains controversial. This study aimed to conduct a meta-analysis on the effect of exercise training on the vascular function of patients with CKD.MethodsEmbase, the Cochrane Central Register of Controlled Trials, and Medline were searched from inception until November 15, 2021. The terms exercise, CKD, dialysis, kidney transplant, and randomized controlled trial (RCT) were searched alone or in combination. RCTs were included when studies compared exercise with active control, usual care, or no intervention, and the studies reported vascular function on patients with CKD.ResultsThis meta-analysis included 18 RCTs with 817 patients. Exercise training was significantly associated with decreased pulse wave velocity weighted mean difference (WMD), −0.56; 95% confidence interval (CI), −1.02 to −0.09, P = 0.02 and augmentation index (WMD, −3.26; 95% CI, −5.46 to −1.05, P = 0.004). It was also significantly associated with improved peak VO2 (WMD, 2.64; 95% CI, 1.94–3.35, P < 0.00001), general health (WMD, 7.03; 95% CI, 0.65–13.42, P = 0.03), and vitality (WMD, 9.1; 95% CI, 2.50–15.69, P = 0.007).ConclusionsThe meta-analysis suggested that exercise training improved vascular function in patients with CKD. An exercise program should be considered as one of the management strategies for vascular dysfunction in patients with CKD. Further studies are needed to demonstrate that exercise training improves cardiovascular diseases in patients with CKD.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Association of Exercise With Vascular Function in Patients With CKD: A Meta-Analysis of Randomized Controlled Trials

Wang

Xie

et al. 2022

Front. Med.

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“…The 12-week, 3times per week intradialytic group exercise programme was conducted around 30 min during the rst 2 hours [4,22,23] of each hemodialysis session, and consisted of aerobic exercise and resistance exercise. Before the puri cation started, the participations would take a 5-minite warm up exercise by muscle stretching.…”

Section: Interventionmentioning

confidence: 99%

Does Intradialytic Group Exercise Influence Malnutrition and Quality of Life in Maintenance Hemodialysis Patients? Evidence From an Experimental Study Using a Single-group Repeated-measures Design

Zhou

Zhang

Shi

et al. 2021

Preprint

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BackgroundMaintenance hemodialysis (MHD) patients is the representative of the sedentary group and often suffer from physical inactivity. Exercise rehabilitation is not widely included in dialysis care despite demonstrated health benefits. This study aimed to evaluate the effectiveness of intradialytic group exercise in MHD patients.MethodsThis was a single center, single-group repeated-measures design study, which included MHD patients in the hemodialysis center in Taizhou, China. The 12-week, 3 times per week intradialytic group exercise programme was conducted around 30 min during the first 2 hours of each dialysis session. Anthropometric indicators, including Body Mass Index (BMI), Triceps Skinfold Thickness (TSF), Mid-upper Arm Circumference (MUAC), Mid-arm Muscle Circumference (MAMC) Handgrip Strength (HGS), and quality of life were measured at baseline, 4-week follow up and 12-week follow up. Laboratory indicators, including Hemoglobin level (Hb), Total Protein (TP) and Albumin (Alb) were measured at baseline and 12-week follow up. The repeated-measures analysis of variance and Friedman test were used to compare the parametric and non‐parametric data at three time points, respectively. Paired t test was used to compare the continuous parametric between two time points.ResultsNinety patients were enrolled at baseline and seventy-five patients finished the whole 12-week exercise programme. There were 7 patients dropped out for losing of motivation and sample churn rate for losing of motivation was 7.8% (7/90). Participants reported significant improvements in most of the outcomes, TSF (F (2, 148) = 28.908, p = 0.000), MUMC (F (2, 148) = 3.1821, p = 0.044), MAMC (F (2, 148) = 27.795, p = 0.000), HGS (F (2, 148) = 42.383, p = 0.000), TP (F (t = -2.417, p = 0.018), ALB (t -3.190, p = 0.002), Hb (t = -2.353, p = 0.021), and QOL (F (2, 148) = 10.48, p = 0.000).ConclusionsThe positive results from this research suggest that intradialytic group exercise programme including aerobic exercise and resistance exercise is a safe and suitable exercise way for maintenance hemodialysis patients. This exercise can help keep patients’ motivation and improve nutritional status and quality of life in maintenance hemodialysis patients.

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Effects of intradialytic exercise on physical performance and cardiopulmonary fitness: promises that need to be confirmed

2021

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Effects of intradialytic cycling exercise on daily physical activity, physical fitness, body composition, and clinical parameters in high-volume online hemodiafiltration patients: a pilot randomized-controlled trial

Cited by 20 publications

References 38 publications

Association of Exercise With Vascular Function in Patients With CKD: A Meta-Analysis of Randomized Controlled Trials

Association of Exercise With Vascular Function in Patients With CKD: A Meta-Analysis of Randomized Controlled Trials

Does Intradialytic Group Exercise Influence Malnutrition and Quality of Life in Maintenance Hemodialysis Patients? Evidence From an Experimental Study Using a Single-group Repeated-measures Design

Effects of intradialytic exercise on physical performance and cardiopulmonary fitness: promises that need to be confirmed

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