Effects of intravenous low-dose recombinant human atrial natriuretic peptide on renal function in the perioperative management for gastrointestinal perforation or ileus: A retrospective single-center study

Maruta, Toyoaki; Otao, Go; Miyazato, Takeshi; Maruta, Nozomi; Yamauchi, Koichiro; Yano, Takao; Kawano, Taro; Tsuneyoshi, Isao

doi:10.1016/j.jcrc.2012.07.020

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Atrial Natriuretic Peptide1

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“…A trend toward reduced need for RRT was observed when ANP was used for prevention but not for treatment. Finally, enhanced renal recovery in a group of patients with an average age above 70 years receiving low-dose ANP during emergency, gastrointestinal surgery has been observed [27]. Additionally, the most recent metaanalysis showed a significant reduction in AKI when ANP was used during cardiovascular surgery in elderly patients (mean age >65 years in the included studies) [23 && ].…”

Section: Atrial Natriuretic Peptidementioning

confidence: 99%

Prevention of renal dysfunction in postoperative elderly patients

Mårtensson

Bellomo

2014

Current Opinion in Critical Care

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The future increase in elderly patients being exposed to surgery calls for improved perioperative management to prevent collaterally increased AKI. Although pharmacological therapies aiming to protect the kidneys from harm are under evaluation, hemodynamic optimization and avoidance of nephrotoxic drugs, including HES and hyperchloremic solutions, are critical for the elderly perioperative patient.

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Section: Atrial Natriuretic Peptidementioning

confidence: 99%