Effects of laying on of hands with and without a spiritual context on pain and functionality of older women with knee osteoarthritis: study protocol for a randomized controlled trial

Effect of laying on of hands as a complementary therapy for pain and functioning in older women with knee osteoarthritis: A randomized controlled clinical trial

“…This is a triple‐blind (ie, blinded assessor, patient and statistician), single‐center, prospective, parallel and randomized controlled trial, registered on clinicaltrials.gov under number NCT02917356. A full detailed description of the methods for this trial can be found in a previous publication 28 . This study was approved by the Research Ethics Committee of the Federal University of Juiz de Fora, Brazil under registry CAAE 52 623 115.0.0000.5147.…”

“…Patients enrolled in all groups participated in a 45‐minute, light‐to‐moderate group kinesiotherapy program consisting of 5‐minute warm‐up and stretching, 37‐minute exercise (strengthening of lower limbs and neuromotor exercise ‐ motor skills and balance), and 3‐minute relaxation (detailed description in Zacaron et al 28 ). The intervention took place twice a week for 8 weeks and was supervised by 6 trained physical therapists blinded to treatment assignment.…”

“…To make control patients feel the presence of someone in the room, they were accompanied by volunteers who moved slowly and randomly to simulate the presence of someone performing LooH. However, there was no intention to heal the patient in this group 28 …”

Dolor en la Artrosis de Rodilla

“…Por otra parte, su liberación, estimula la liberación de más mediadores. [25][26][27] La activación de los nociceptores genera señales a través de las fibras mielinizadas A-δ y/o las fibras no mielinizadas C, las que se dirigen a la región dorsal de la médula espinal. Las fibras A-δ transmiten el dolor agudo y las fibras C el difuso (►Fig.…”

Comparative intra-articular gene transfer of seven adeno-associated virus serotypes reveals that AAV2 mediates the most efficient transduction to mouse arthritic chondrocytes

“…Osteoarthritis (OA) is one of the most common forms of arthropathy, affecting more than 10% of adults with higher rate in women than in men, and provoking considerable pain and disability [1,2]. Currently available studies attribute the pathogenesis of OA partially to dysregulation of extracellular matrix (ECM) metabolism and the reduction of chondrocytes [3].…”