Effects of Left Ventricular Assist Device Therapy on Ventricular Arrhythmias

Abstract

After LVAD placement, there is a significant rise in the incidence of de novo MVT. By contrast, the incidence of PVT/VF was unaffected by LVAD placement.

Ventricular Arrhythmias After Left Ventricular Assist Device

“…6 Similar findings have been seen in single-center observational studies, where VA have been reported to occur in 22% to 59% of LVAD recipients (Table). 6,[10][11][12][13][14][15][16][17][18] Incident VAs are also seen in patients who have not had VA before LVAD implant. Ziv et al 14 retrospectively studied 91 consecutive patients who underwent implant of a firstgeneration Heartmate XVE device.…”

Cytoskeletal Basis of Ion Channel Function in Cardiac Muscle

“…6 An early postoperative period study after cardiac unloading therapy in 17 HF patients showed that in the first two weeks after LVAD implantation, HF was associated with a relatively high incidence of ventricular arrhythmias associated with QTc interval prolongation 7 . In addition, a recent retrospective study of 100 adult patients with advanced HF, treated with an axial-flow HeartMate LVAD suggested that the rate of new-onset monomorphic ventricular tachycardia (MVT) was increased in LVADtreated patients compared to patients given only medical treatment, while no effect was observed on the development of polymorphic ventricular tachycardia (PVT)/ventricular fibrillation (VF) 8 .…”

Asistencia ventricular mecánica como puente al trasplante en pacientes en shock cardiogénico: Experiencia preliminar en Chile con ABIOMED BVS 5000®

“…Por otro lado, las infecciones relacionadas a dispositivos son frecuentes, con una incidencia cercana a 50% 16,17 . También se ha descrito una mayor incidencia de taquicardia ventricular monomorfa, especialmente en la primera semana posimplante 18 .…”