2023
DOI: 10.3389/fpsyt.2023.1196113
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Effects of long-term exposure to high altitude on brain structure in healthy people: an MRI-based systematic review and meta-analysis

Abstract: PurposeTo conduct a systematic review and meta-analysis of observational studies of brain MRI, this paper assesses the effects of long-term exposure to high-altitude on brain structures in healthy people.MethodsObservational studies related to high-altitude, brain and MRI were systematically searched based on data retrieved from PubMed, Embase and Cochrane Library. The timescale for collecting literature was from the establishment of the databases to 2023. NoteExpress 3.2 was used to manage the literature. Two… Show more

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Cited by 4 publications
(1 citation statement)
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“…In high‐altitude areas, the lower air pressure causes oxygen particles to be more spread out. Therefore, when people breathe in, they encounter inadequate oxygenation in their blood and lungs (Luo et al., 2023 ). Even though the brain constitutes only around 2% of the body's weight, it utilizes 20% of the oxygen the body takes in (Raichle & Gusnard, 2002 ).…”
Section: Introductionmentioning
confidence: 99%
“…In high‐altitude areas, the lower air pressure causes oxygen particles to be more spread out. Therefore, when people breathe in, they encounter inadequate oxygenation in their blood and lungs (Luo et al., 2023 ). Even though the brain constitutes only around 2% of the body's weight, it utilizes 20% of the oxygen the body takes in (Raichle & Gusnard, 2002 ).…”
Section: Introductionmentioning
confidence: 99%