Anticipating the consequences of climatic change for re requires understanding of the causes of variation in historical re regimes. We assessed the in uence of annual and decadal variation in climate on re regimes of ponderosa pine-dominated forests in eastern Oregon and Washington using existing, annually dated tree-ring reconstructions . In four watersheds, we compared the extent of low-severity res (total area burned each year) to precipitation and the Southern Oscillation Index, a measure of variation in El Niño-Southern Oscillation (ENSO), which affects weather in this region. At the annual scale, large res burned during dry years and El Niño years (low SOI) in all watersheds while small res burned regardless of variation in these climate parameters. Large res also burned during relatively wet years and La Niña years (high SOI) in one watershed, indicating that local factors can override regional climate controls in some locations. Climate from previous years did not in uence current year's re extent. The in uence of ENSO on re regimes in this region has not previously been demonstrated at these multicentury, regional scales. At the decadal scale, re extent varied with precipitation, perhaps in response to variation in such climate features as the Paci c Decadal Oscillation. Several decades of low re extent in the watersheds during the early 1800s was synchronous with a lack of re at other sites in North and South America, probably in response to a change in the global climate that included a lessening in the frequency and/or intensity of ENSO events.