2024
DOI: 10.1002/jum.16468
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Effects of Low‐Intensity Pulsed Ultrasound on the Regulation of Free Fatty Acid Release in 3T3‐L1 Cells

Liu Wu,
Xinfang Xiao,
Juan Deng
et al.

Abstract: ObjectivesTo investigate the effects of low‐intensity pulsed ultrasound (LIPUS) on the proliferation, differentiation, and tumor necrosis factor‐α (TNF‐α)‐induced lipolysis of 3T3‐L1 cells, and to explore the feasibility of regulating the release of free fatty acids (FFA) to prevent lipotoxicity.MethodsDifferent intensities (30, 60, 90, and 120 mW/cm2) of LIPUS were applied to 3T3‐L1 preadipocytes for different durations (5, 10, 15, 20, 25, and 30 minutes). Appropriate parameters for subsequent experiments wer… Show more

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