2003
DOI: 10.1016/s1532-0456(03)00110-8
|View full text |Cite
|
Sign up to set email alerts
|

Effects of mercury on myosin ATPase in the ventricular myocardium of the rat

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

2
26
0
1

Year Published

2004
2004
2023
2023

Publication Types

Select...
7

Relationship

0
7

Authors

Journals

citations
Cited by 34 publications
(29 citation statements)
references
References 38 publications
2
26
0
1
Order By: Relevance
“…Tetanic stimulation obtained after inhibition of sarcoplasmic reticulum activity with caffeine or ryanodine has been used to produce maximal activation of the contractile machinery in the intact myocardium (29,30). Caffeine acts by emptying the sarcoplasmic reticulum of its calcium content and the sustained exposure to caffeine prevents sarcoplasmic reticulum Ca 2+ accumulation (31).…”
Section: Discussionmentioning
confidence: 99%
“…Tetanic stimulation obtained after inhibition of sarcoplasmic reticulum activity with caffeine or ryanodine has been used to produce maximal activation of the contractile machinery in the intact myocardium (29,30). Caffeine acts by emptying the sarcoplasmic reticulum of its calcium content and the sustained exposure to caffeine prevents sarcoplasmic reticulum Ca 2+ accumulation (31).…”
Section: Discussionmentioning
confidence: 99%
“…[31], due most probably to all the differences in the methodology (origin of cells, amount of MTBHSP70 used for stimulation, LPS removal strategy). Indeed, differences in the responses to LPS have been reported for bone marrow-versus monocyte-derived dendritic cells [32]. Opposite responses have been reported for treatment with high-versus low-dose HSP [15], and even for treatment with different peptides of MTBHSP70 [33].…”
Section: Discussionmentioning
confidence: 99%
“…Responses were compared only among patients diagnosed with the same disease. For some experiments, blood was also obtained from healthy control volunteers who worked in the laboratory (mean age = 28, range [20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35] Peripheral blood mononuclear cell isolation Twenty ml of peripheral blood was collected by venepuncture in the morning (between 8 and 10 a.m) and samples stored into heparinized tubes. Synovial fluid (approximately 10 ml) was collected from all patients and diluted immediately 4 : 3 with phosphate buffered saline (PBS) and 15 m M EDTA before analysis.…”
Section: Subjectsmentioning
confidence: 99%
“…Mercury (Hg) is a heavy metal that affects the activity of the normal function of several enzymes, ion channels or receptors (Moreira et al, 2003). Exposure to toxic mercury is a growing health hazard throughout the world today.…”
Section: Introductionmentioning
confidence: 99%
“…The toxicity of high doses of inorganic mercury on the central nervous system and urinary system has been known for decades (Patrick, 2002). However, few data are available on the effect of mercury on heart and aorta tissues (Boffetta et al, 2001;Moreira et al, 2003). Inorganic mercury is conjugated with glutathione in the liver and secreted in the bile as a cysteine mercury or glutathione mercury complex (Boffetta et al, 2001).…”
Section: Introductionmentioning
confidence: 99%