Effects of Metal Poisoning on Five Liver Enzymes in the Killifish (Fundulus heteroclitus)

Abstract

Activities of five liver enzymes (acid and alkaline phosphatase, catalase, xanthine oxidase, and ribonuclease) from Fundulus heteroclitus surviving exposure to 96-hr TLm concentrations of salts of six metals (lead, copper, mercury, beryllium, cadmium, and silver) differed markedly from those of unexposed fish. Changes in enzyme activity produced by the exposures were not necessarily the same in magnitude or direction as those observed when the salts were introduced directly into the enzyme preparations. It is proposed that changes in liver enzyme activity may be useful as a kind of biochemical autopsy tool for diagnosing sublethal metal poisoning in fish.

Determination of acute toxicity levels of mercury to the fishTilapia mossambica (Peters)

“…Jackim et al (1970) and Klaunig et al (1975) reported relatively high acute 96-hr LC", of mercury (as mercuric chloride) to adult mummichog, Fundulus heteroclitus of 23D and 2010 pg/l respectively. Both the studies were performed under similar laboratory conditions, utilising the fish collected during the spring and summer months.…”

Comparative Studies on the Effects of Herbicide Atrazine on Freshwater Fish Oreochromis niloticus and Chrysichthyes auratus at Assiut, Egypt

“…Moreover, atrazine has harmful effects on spleen. liver and anterior kidney (Jackim et al 1970 andRehwoldt 1978). Otherwise, Kettle et al (1987) have shown that atrazine has an inhibitory effect on macrophyte communities as photosynthesis inhibitor.…”

Cadmium‐induced histomorphological changes in the testis and pituitary gonadotrophic hormone secreting cells of the cyprinidPuntius sarana

“…Toxic effects of cadmium in fishes have been exten* sively studied (Schweiger, 1957;Gardner & Yevich, 1969Eisler & Gardner, 1973;Eisler, 1974); however, the pathological effects on the gonads and pituitary gland have received only scarce attention (Jackim et al, 1970;Sangalang & O'Halloran, 1972;Larson, 1975;Sjobeck & Larson, 1978). The aim of this investigation is to examine, in the cyprinid Puntius sarana, the histopathological effects of cadmium chloride (CdCl 2 ) on testes and pituitary GTH cells, and the capability of this fish to recovery from these effects.…”