Effects of mixed-technology CO2 and Ga-As laser in patients with hidradenitis suppurativa–A case series

Lindén, Olof; Lönndahl, Louise; Erlendsson, Andrés M.; Sandberg, Catarina; Killasli, Hassan

doi:10.1016/j.jdcr.2022.10.022

Cited by 3 publications

(3 citation statements)

References 5 publications

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“…The use of CO 2 laser has also been reported in combination with other lasers. In one study, the combination of ablative fractional CO 2 laser and non-ablative fractional Ga–As laser (1540 nm) was used for eight patients who had previously failed topical treatment and at least one systemic treatment [ 31 ]. All eight patients reported improvement, with one patient demonstrating complete improvement after six treatments.…”

Section: Resultsmentioning

confidence: 99%

Emerging Treatments and the Clinical Trial Landscape for Hidradenitis Suppurativa—Part II: Procedural and Wound Care Therapies

Fragoso,

Masson,

Gillenwater

et al. 2023

Dermatol Ther (Heidelb)

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Procedural treatments are a cornerstone of hidradenitis suppurativa (HS) management. New interventional therapies are being studied as part of the upsurge in HS research and clinical trials. Additionally, draining wounds can impart a significant negative impact on patients’ quality of life, requiring daily dressing changes. However, standardized guidelines on how to best manage HS wounds both day-to-day and post-procedure are lacking. In part II of this emerging therapies review, procedural treatments and wound care dressings and devices that are being investigated for HS management are discussed.

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Section: Resultsmentioning

confidence: 99%

Emerging Treatments and the Clinical Trial Landscape for Hidradenitis Suppurativa—Part II: Procedural and Wound Care Therapies

Fragoso,

Masson,

Gillenwater

et al. 2023

Dermatol Ther (Heidelb)

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“…The Nd:YAG laser is a nonablative laser that works by emitting light waves of different wavelength that create high-energy states, which produce heat and lead to the destruction of cells 16 . In HS, the Nd:YAG laser targets hair shafts and follicles via absorption by melanin and water chromophores and works effectively in superficial and deep layers of the skin 16,17 . On the other hand, the Alexandrite laser works by damaging the bulge stem cells and dermal papilla of hair follicles by targeting melanin and acting as a target chromophore 16 …”

mentioning

confidence: 99%

“…16 In HS, the Nd:YAG laser targets hair shafts and follicles via absorption by melanin and water chromophores and works effectively in superficial and deep layers of the skin. 16,17 On the other hand, the Alexandrite laser works by damaging the bulge stem cells and dermal papilla of hair follicles by targeting melanin and acting as a target chromophore. 16 The advantage of laser therapies includes targeting a specific area of the body where HS is present without significant systemic adverse effects, complications, or antibiotic resistance.…”

mentioning

confidence: 99%

A Retrospective Review of Laser Therapy for Treatment of Hidradenitis Suppurativa

Fortoul,

Macias Martinez,

Ventura Rodriguez

et al. 2023

Ann Plast Surg

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Purpose Hidradenitis suppurativa (HS) is a chronic inflammatory disease characterized by painful and foul-smelling cystic nodules and sinus tracts in the apocrine gland-bearing regions. The treatment options include topical, intralesional, systemic, and surgical modalities. Currently, the most novel therapy is laser therapy to provide localized treatment without systemic adverse effects. However, data regarding patient outcomes after laser treatment are limited because of the low prevalence of this disease. This study aimed to evaluate the efficacy of laser therapy as a treatment modality for patients with HS. Methods A retrospective review cohort analysis of patients with HS undergoing laser treatment between 2016 and 2021 was conducted. Patient demographics, lesion location(s), Hurley stage, age of onset and diagnosis, treatment length, type, outcomes, and complications were analyzed. Results Ninety-four patients met the inclusion criteria; on average, patients were treated with 5.8 laser sessions for 14.8 months with no complications and minor blood loss. Hidradenitis suppurativa progression commonly starts during puberty, with a median onset of 13.8 years and diagnosis of HS at 16.2 years. All patients (n = 94) showed an improvement in HS disease severity: 59.6% completed treatment, 12.0% are currently undergoing treatment, and 26.0% were lost to follow-up. Conclusions Laser therapy is an effective and safe therapy for HS leading to improved quality of life and should be considered in the treatment and management of HS.

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Intralesional hyaluronidase as a treatment for fibrosis in hidradenitis suppurativa: a case report

Dursun,

Altay,

Temiz

2024

Int J Dermatology

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Effects of mixed-technology CO2 and Ga-As laser in patients with hidradenitis suppurativa–A case series

Cited by 3 publications

References 5 publications

Emerging Treatments and the Clinical Trial Landscape for Hidradenitis Suppurativa—Part II: Procedural and Wound Care Therapies

Emerging Treatments and the Clinical Trial Landscape for Hidradenitis Suppurativa—Part II: Procedural and Wound Care Therapies

A Retrospective Review of Laser Therapy for Treatment of Hidradenitis Suppurativa

Intralesional hyaluronidase as a treatment for fibrosis in hidradenitis suppurativa: a case report

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