Effects of Nasal Pressure Support on Ventilation and Inspiratory Work in Normocapnic and Hypercapnic Patients With Stable COPD

The Impact of Noninvasive Ventilation During the Physical Training in Patients With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (Copd)

“…Other studies, which have investigated the role of NIV associated with physical training, have also shown beneficial effects, such as better exercise tolerance, 18,28,29 a reduction in dyspnea, 18 an increase in arterial oxygenation, 28 and an increase in respiratory muscle strength. 17,30,31 In this study, we found that only the group that underwent PT with BiPAP ® ventilation support had a significant reduction in SBP, HR, and blood lactate at the same intensity of exercise. The attenuation of these cardiovascular responses can be explained by the increase in muscular oxidation capacity, slowing the cardiovascular adjustments through metaboreflex response.…”

“…It is believed that positive pressure is available during the auxiliary inspiratory phase of ventilation in the patient and reduces the work of the respiratory musculature, diminishing the intrinsic positive end expiratory pressure (PEEPi) through the constant application of expiratory support. [14][15][16][17] Costes et al 18 conducted a physical training program using an ergometric bicycle for 8 weeks associated with NIV (BiPAP ® ) and observed a significant increase in the oxygen consumption (VO 2 ) compared to physical training alone. However, Bianchi et al 19 did not find additional effects from proportional assisted ventilation support when associated with a physical training program for patients with COPD.…”

Real time noninvasive estimation of work of breathing using facemask leak-corrected tidal volume during noninvasive pressure support: validation study

“…WOB and patient effort decreased on average by 60 % at inspiratory PS settings of approximately 15 cm H 2 O and there were near uniform decreases in dyspnea scores [15]. At noninvasive ventilation settings that provided maximum efficacy, WOB was reduced to a range of 5.4-10.2 J/min (essentially the normal adult range) [4,[16][17][18]. In patients with acute lung injury, noninvasive PS was shown to reduce neuromuscular drive, unload inspiratory muscles, and improve dyspnea [4].…”

Spinal anaesthesia and non-invasive positive pressure ventilation for hip surgery in an obese patient with advanced chronic obstructive pulmonary disease

“…This is in comparison with continuous positive airway pressure, which has been shown not to improve ventilatory parameters in the short term, and requires much longer application. 11 Spinal and epidural anaesthesia are beneficial for both obese and advanced COPD patients. Compared with general anaesthesia, the maintenance of spontaneous breathing means there is less cephalad displacement of the diaphragm and less risk of atelectasis.…”