Effects of Natural Products on Body Weight and Biochemical Parameters in Healthy Rats

Abstract

The present study was undertaken to evaluate effect of natural products i.e. Anthocephalus indicus; KADAM, roots, Hibiscus rosa sinensis roots, Tinospora cordifolia stem and Cassia tora seeds in normal healthy rats. In this study ethanol extract of above mentioned medicinal plants had macerated with aqueous gum acacia (2%, w/v) suspension and fed orally (500 mg/kg bw p.o.) to male adult healthy normal rats of Charles Foster strain for 30 days. Results of this study showing that alcoholic extracts caused no any signicant reduction in blood glucose, total cholesterol, triglyceride, phospholipids, free fatty acid, lipid peroxide and no signicant increased in post heparin lipolytic activity, but on the other hand as per pre-existing data and my published studies in diabetic patients and diabetic experimental animals showed that extracts exerting all above effects signicantly. That's why it is very clear here if healthy person will take natural products, it never cause hypoglycemia, hypolipidemia and under weight. Natural products also not cause any signicant change on hepato-specic parameters. Thus from this study we conclude that, natural products are safe, non toxic and free from side effects, in comparison to synthetic drugs.

Untitled

“…Tehran first demonstrated elevation of minor hemoglobin in diabetes mellitus introduced the column method of separating out the fast hemoglobin, pointed out that HbA 1 C is related to control of diabetes. The advantages of Gly Hb estimation are those of a simple procedure, lack of any need for dietary preparation or for fasting, elimination of the variability usually found an oral glucose tolerance tests as well as an accurate reflection of overall chronic hyperglycemia [98][99][100][101] .…”

Shelf Life Enhancement of Button Mushroom (Agraricus Bisporus) by Modified Atmosphere Packaging (Map)

“…Fresh button mushrooms (Agaricus bisporus) treatment with solution of 1.5% CaCl2 + 0.5% citric acid and stored for 16 days at 12°C. The report states that post-harvest chemical treatment maintained better firmness, weight, color and inhibit cellulase, beta-1, 3 glucanase, chitinase and phenylalanine ammonialyase activities [16]. [17] found that CaCl2 treated mushrooms packaged under MAP experienced lowest weight loss and L value (brightness), highest degree of overall color change (ΔE) and glucose contents.…”

Untitled

“…Furthermore, hyperlipidemia may also induce abnormalities like oxidation of lipids, the formation of ketone bodies as well as resistance to insulin in muscle and liver cells in diabetic patients. Treatment of hyperlipidemia with available lipid-lowering drugs: fibrates and bile acid sequestrants are not free from many side effects such as myositis, gastrointestinal upset along with elevated hepatic, renal function tests [11][12][13][14][15][16][17] .…”