Effects of near-infrared low-level laser irradiation on microcirculation

Abstract

The circulatory changes observed seemed to be mediated largely by LLLI-induced reduction of [Ca2+]i in VSMCs, in addition to the involvement of NO in the initial phase.

He‐Ne laser effects on blood microcirculation during wound healing: A method of in vivo study through laser Doppler flowmetry

“…The presented results, in comparing groups LG and LCG, would seem to be at variance with the positive findings reported by the use of lasers with the same or different wavelengths on microcirculation effects [2,4,5,15,27]. However, it should be noted that results from such studies are not exclusively positive.…”

“…On the 2nd and 3rd days the measurements performed were IR, 7 minutes and FR; and then SR were performed on the 7th, 14th, and 21st days. The measurements performed at 7 and 20 minutes after laser exposure were performed to investigate immediate effects of laser [2].…”

“…On the other hand, Maegawa et al [2] reported an immediately induced arteriolar vasodilatation in rat's mesentery, by the use of LILT, and this finding was not associated with a rise in temperature provoked by the irradiation.…”

“…There are several reports documenting significant positive effects of low-intensity laser therapy (LILT) on biological systems [1][2][3][4][5][6][7]. However, this therapy has yet to gain wide acceptance in the medical community.…”

“…Several reports demonstrated that LILT and blood flow effects in vivo are related to wavelengths longer than 780 nm [1,2,[4][5][6][7][8]. In vitro studies with wavelengths between 632.8 and 660 nm showed effects on blood cells, such as changes in erythrocyte aggregation and increased proliferation of lymphocytes [9][10][11].…”