Effects of neural mobilization in disorders associated with chronic secondary musculoskeletal pain: A systematic review and meta-analysis

Evaluation of In Vivo Biocompatibility in Preclinical Studies of a Finger Implant Medical Device Correlated with Mechanical Properties and Microstructure

“…These joints are often affected by osteoarthritis, a degenerative condition that causes deterioration of the joint surfaces and eventual bone modeling. The consequence of such a condition is severe pain, leading to significant functional limitations and disability, as well as a significant social burden. − Patients with osteoarthritis represent the cohort of people with upper limb osteoarthritis most likely to undergo surgical intervention . However, previous studies evaluating the efficacy of surgical intervention have shown varying levels of benefit in terms of pain reduction and improved function and have reported adverse event rates ranging from 10 to 22%, depending on the procedure used .…”

“…1−4 Patients with osteoarthritis represent the cohort of people with upper limb osteoarthritis most likely to undergo surgical intervention. 5 However, previous studies evaluating the efficacy of surgical intervention have shown varying levels of benefit in terms of pain reduction and improved function and have reported adverse event rates ranging from 10 to 22%, depending on the procedure used. 6 Therefore, it is important to identify the most effective management strategies to improve pain and function in the osteoarthritis population.…”

Effectiveness of Neural Mobilisation on Pain Intensity, Functional Status, and Physical Performance in Adults with Musculoskeletal Pain – A Systematic Review with Meta-Analysis

“…[93][94][95][96] For functional status and cervical range of motion, there were no significant differences between groups, which agrees with the findings of Varangot-Reille et al 19 It was not possible to perform meta-analyses for the other musculoskeletal conditions and outcomes, such as pressure pain threshold and muscle strength, which limits the conclusions to be drawn. González-Matilla et al 18 identified an effectiveness of neural mobilisation when compared to joint mobilisation and exercises for pain intensity in people with autoinflammatory diseases (hand osteoarthritis and rheumatoid arthritis), but they showed a pooled global effect for both conditions. 87 Our analyses revealed no statistical significance for pain improvement in any of these conditions individually.…”

“…• Population -People over 18 We searched for articles published until June 2023 in the data sources described in Table 1. The search was performed by one reviewer (FB).…”

“…Previous reviews have investigated the effectiveness of neural mobilisation mainly in nerverelated musculoskeletal disorders, 8,[15][16][17][18][19] but evidence on its effectiveness in musculoskeletal pain conditions without neurological impairments, as well as in aspects of physical performance, is sparse. Thus, this systematic review aims to investigate up-to-date evidence on the effectiveness of neural mobilisation techniques in improving pain, function, and physical performance in people with different musculoskeletal pain conditions without neurological deficits.…”