Effects of neuromodulation on cognitive and emotional responses to psychosocial stressors in healthy humans

Moses, Tabitha E.H.; Gray, Elizabeth; Mischel, Nicholas; Greenwald, Mark K.

doi:10.1016/j.ynstr.2023.100515

Cited by 15 publications

(6 citation statements)

References 369 publications

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“…Therefore, a scalable multiterminal memristor with only one set of signal generators can be designed to realize such specific functions. For example, the OOP electrode pairs in Device 2 and Device 4 can simulate the effect of neuromodulatory systems, which provide a foundation for cognitive functions such as attention, emotion, goal-directed behavior, and decision-making in higher organisms. , This will help to reduce the difficulty of circuit design and be convenient for the development of memristor-integrated circuits to realize AI computing.…”

Section: Resultsmentioning

confidence: 99%

Computational Study on Interlocked-Ferroelectricity-Contributed High-Performance Memristors Based on Two-Dimensional van der Waals Ferroelectric Semiconductors

Chen,

Li,

Kong

et al. 2024

ACS Appl. Mater. Interfaces

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In order to realize the prevailing artificial intelligence technology, memristorimplemented in-memory or neuromorphic computing is highly expected to break the bottleneck of von Neumann computers. Although high-performance memristors have been vigorously developed in labs or in industry, systematic computational investigations on memristors are seldom. Hence, it is urgent to provide theoretical or computational support for the exploration of memristor operating mechanisms or the screening of memristor materials. Here, a computational method based on the main input parameters learned from the first-principles calculations was developed to measure resistance switching of two-terminal memristors with sandwiched metal/ ferroelectric semiconductor/metal architectures, which strikingly agrees with the experimental measurements. Based on our developed method, the diverse multiterminal memristors were designed to fully exploit the application of interlocked ferroelectricity of a ferroelectric semiconductor and realize their heterosynaptic plasticity, and their heterosynaptic behaviors can still be well described. Our developed method can provide a paradigm for the emulation of ferroelectric memristors and inspire subsequent computational exploration. Furthermore, our study also supplies a device optimization strategy based on the interlocked ferroelectricity and easy processing of two-dimensional van der Waals ferroelectric semiconductors, and our proposed heterosynaptic memristors still await further experimental exploration.

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Section: Resultsmentioning

confidence: 99%

Computational Study on Interlocked-Ferroelectricity-Contributed High-Performance Memristors Based on Two-Dimensional van der Waals Ferroelectric Semiconductors

Chen,

Li,

Kong

et al. 2024

ACS Appl. Mater. Interfaces

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“…NAc-DBS effectively enhances mood ( Nauczyciel et al, 2013 ; Synofzik et al, 2012 ) b by regulating dopamine release in the NAc, a key region closely linked to emotional, cognitive ( Moses et al, 2023 ), and motor systems ( Nicola et al, 2005 ). Previous studies in animal models and humans have revealed disrupted FC within the dopaminergic pathway in MDD patients ( Bearden et al, 2009 ; Genzel et al, 2015 ; Godsil et al, 2013 ), with reduced synchronization of brain regions in the mesolimbic and mesocortical pathways ( Schoenfeld et al, 2014 ).…”

Section: Discussionmentioning

confidence: 99%

Nucleus accumbens deep brain stimulation improves depressive-like behaviors through BDNF-mediated alterations in brain functional connectivity of dopaminergic pathway

Li,

Lo,

Tseng

et al. 2023

Neurobiology of Stress

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“…Stress response promotes energy production, metabolic changes, digestive and reproductive system suppression, and immune system activation. 21 Stress https://doi.org/10.2147/JMDH.S468878…”

Section: Stress Response Physiologymentioning

confidence: 99%

Ocular Surface Health in Connection with Anxiety and Depression: a Review

Alkozi

2024

JMDH

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Psychosomatic ophthalmology emerged after World War II because patients attended clinics with symptoms that were not explained by physiological findings, subsequently it became clear that psychological distress could be associated with several ocular disorders, including dry eye syndrome. Dry eye disease is a common disorder with increasing prevalence due to environmental factors such as pollution, smoking, and sleep disorders. The burden of dry eye disease affects both patients and society, making it a very important target for investigation. Numerous studies showed that dry eye disease prevalence including the severity of the symptoms of dry eye is higher in patients suffering from depression and/or anxiety. Some studies suggest the implication of serotonin in tears being dysregulated by the disorders. The current review highlights the evidence of the association between anxiety, depression, and dry eye disease and summarizes the recent advances in research in this area, together with a brief explanation of the physiology of stress that could lead to psychological disorders.

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Effects of neuromodulation on cognitive and emotional responses to psychosocial stressors in healthy humans

Cited by 15 publications

References 369 publications

Computational Study on Interlocked-Ferroelectricity-Contributed High-Performance Memristors Based on Two-Dimensional van der Waals Ferroelectric Semiconductors

Computational Study on Interlocked-Ferroelectricity-Contributed High-Performance Memristors Based on Two-Dimensional van der Waals Ferroelectric Semiconductors

Nucleus accumbens deep brain stimulation improves depressive-like behaviors through BDNF-mediated alterations in brain functional connectivity of dopaminergic pathway

Ocular Surface Health in Connection with Anxiety and Depression: a Review

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